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46232

Supelco

Dipyron hydrate

VETRANAL®, analytical standard

Synonyme(s) :

Metamizol, Methapyrone

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About This Item

Formule empirique (notation de Hill):
C13H16N3NaO4S · H2O
Numéro CAS:
5907-38-0
Poids moléculaire :
351.35
Numéro Beilstein :
3865381
Numéro MDL:
MFCD00150293
Code UNSPSC :
41116107
ID de substance PubChem :
329757107
Nomenclature NACRES :
NA.24

Qualité

analytical standard

Niveau de qualité

200

Gamme de produits

VETRANAL®

Durée de conservation

limited shelf life, expiry date on the label

Technique(s)

HPLC: suitable
gas chromatography (GC): suitable

Application(s)

clinical
forensics and toxicology
pharmaceutical (small molecule)

Format

neat

Température de stockage

2-8°C

Chaîne SMILES 

O.[Na+].CN(CS([O-])(=O)=O)C1=C(C)N(C)N(C1=O)c2ccccc2

InChI

1S/C13H17N3O4S.Na.H2O/c1-10-12(14(2)9-21(18,19)20)13(17)16(15(10)3)11-7-5-4-6-8-11;;/h4-8H,9H2,1-3H3,(H,18,19,20);;1H2/q;+1;/p-1

Clé InChI

UNZIDPIPYUMVPA-UHFFFAOYSA-M

Informations sur le gène

human ... PTGS1(5742) , PTGS2(5743)

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Description générale

Metamizol is an active pharmaceutical ingredient with both analgesic and antipyretic effects, primarily used to relieve pain caused by neuritis and neuralgia.

Application

Metamizol may be used as a reference standard for the determination of metamizol in pharmaceutical formulations by reversed-phase high-performance liquid chromatography (RP-HPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Informations légales

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictogrammes

Health hazard
GHS08

Mention d'avertissement

Warning

Mentions de danger

H361fd

Classification des risques

Repr. 2

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificats d'analyse (COA)

Lot/Batch Number
BCCD4172
BCBV3904
SZBC233XV
SZBC208XV
SZB9104XV

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Consulter la Bibliothèque de documents

Simultaneous Determination Of Metamizole, Thiamin And Pyridoxin In Multicomponent Tablet by RP-HPLC.
Chotimah C.
Journal of Food and Pharmaceutical Sciences, 2(3) (2014)
Natália Amanda Gomes et al.
Archives of oral biology, 122, 105000-105000 (2020-12-12)
This study aimed to compare the impact of testosterone and estrogen replacement therapy on mandibular bone density and bone-related markers. Forty male adult rats were randomly allocated to 4 experimental groups (n = 10/group): Sham (Control); Orchiectomy; Orchiectomy plus testosterone replacement; and
Tina Kirchner et al.
Mediators of inflammation, 2012, 849136-849136 (2012-04-07)
The formation of neutrophil extracellular traps (NETs) depends on the generation of reactive oxygen species (ROS). Previous studies revealed that both NADPH oxidase and myeloperoxidase (MPO) are required for NET release. However, the contribution of various ROS as well as
Sylwia Magiera et al.
Journal of AOAC International, 97(6), 1526-1537 (2015-01-30)
A rapid and sensitive ultra-HPLC/MSIMS (UHPLC/MSIMS) assay method for the simultaneous determination in human urine of 22 drugs belonging to different pharmaceutical groups was developed. The drugs were extracted from urine samples and then separated on a Zorbax Rapid Resolution

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