301310
2-Ethyl-2-thiopseudourea hydrobromide
98%
Synonyme(s) :
S-Ethylisothiourea hydrobromide
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About This Item
Formule linéaire :
C2H5SC(=NH)NH2 · HBr
Numéro CAS:
Poids moléculaire :
185.09
Numéro MDL:
Code UNSPSC :
12171500
ID de substance PubChem :
Produits recommandés
Pureté
98%
Forme
powder or crystals
Pf
88-90 °C (lit.)
Application(s)
diagnostic assay manufacturing
hematology
histology
Température de stockage
room temp
Chaîne SMILES
Br.CCSC(N)=N
InChI
1S/C3H8N2S.BrH/c1-2-6-3(4)5;/h2H2,1H3,(H3,4,5);1H
Clé InChI
SWXXKWPYNMZFTE-UHFFFAOYSA-N
Application
Reagent used in the synthesis of pyrimidines.
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 3
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Équipement de protection individuelle
Eyeshields, Gloves, type N95 (US)
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W K Alderton et al.
The Biochemical journal, 332 ( Pt 1), 195-201 (1998-05-13)
Nitric oxide synthases (NOS) have a bidomain structure comprised of an N-terminal oxygenase domain and a C-terminal reductase domain. The oxygenase domain binds haem, (6R)-5,6,7,8-tetrahydro-l-biopterin (tetrahydrobiopterin) and arginine, is the site where nitric oxide synthesis takes place and contains determinants
Mihoko N Nakashima et al.
Journal of pharmacological sciences, 91(1), 47-52 (2003-04-11)
The possible role of nitric oxide (NO) in anxiety following transient cerebral ischemia by a 10-min bilateral carotid occlusion was examined in mice. Two days after the ischemia, mice showed a significant decrease in time spent on the open arms
E Alhan et al.
The European journal of surgery = Acta chirurgica, 164(9), 697-702 (1998-09-05)
To investigate the effects of the constitutive nitric oxide (NO) synthase inhibitor NG-nitro-L-arginine methyl ester (L-Name) and the inducible NO synthase inhibitor amino ethyl-isothiourea (AE-ITU) on acute necrotising pancreatitis (ANP) in rats. Laboratory study. Medical school, Turkey. Morbidity, mortality, effects
T Muraki et al.
Japanese journal of pharmacology, 70(3), 269-271 (1996-03-01)
By dye leakage in mouse skin, we evaluated the inhibition of proinflammatory stimuli-induced plasma extravasation by a putative inhibitor of inducible nitric oxide synthase, S-ethylisothiourea. A low dose of S-ethylisothiourea (5 micrograms/kg) mimicked aminoguanidine in inhibiting the plasma extravasation elicited
R L Rairigh et al.
The Journal of clinical investigation, 101(1), 15-21 (1998-02-14)
Nitric oxide (NO) produced by NO synthase (NOS) modulates fetal pulmonary vascular tone and contributes to the fall in pulmonary vascular resistance (PVR) at birth. Although the inducible (type II) NOS isoform is present in human and rat fetal lungs
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