247588

Salicylic acid

ACS reagent, ≥99.0%

• Synonyme(s) : 2-Hydroxybenzoic acid
• Formule linéaire : 2^-(HO)C₆H₄CO₂H
• Numéro CAS: 69-72-7
• Poids moléculaire : 138.12
• Numéro Beilstein : 774890
• Numéro CE : 200-712-3
• Numéro MDL: MFCD00002439
• Code UNSPSC : 12352100
• ID de substance PubChem : 24854876
• Nomenclature NACRES : NA.21

Propriétés

• Qualité: ACS reagent
• Niveau de qualité: 200
• Densité de vapeur: 4.8 (vs air)
• Pression de vapeur: 1 mmHg ( 114 °C)
• Pureté: ≥99.0%
• Impuretés: H₂SO₄, passes test (darkened)
• Résidus de calcination: ≤0.01%
• Point d'ébullition: 211 °C (lit.)
• Pf: 158-161 °C (lit.)
• Traces d'anions: chloride (Cl^-): ≤0.001%; sulfate (SO₄^2-): ≤0.003%
• Traces de cations: Fe: ≤2 ppm; heavy metals (as Pb): ≤5 ppm
• Chaîne SMILES: OC(=O)c1ccccc1O
• InChI: 1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)
• Clé InChI: YGSDEFSMJLZEOE-UHFFFAOYSA-N
• Informations sur le gène: human ... ALB(213) , PTPN1(5770)

Description

Description générale

Salicylic acid is mainly used as the precursor to synthesize aspirin, a commonly used analgesic and antipyretic. Due to its keratolytic action, it is also used in topical ointments.

Application

Salicylic acid has been used:

• as one of the chemical compound in exposure-based validation of in vitro gastrulation model employed in developmental toxicity screening assays
• as a reference standard in salicylate quantification by reverse-phase high-performance liquid chromatography (RP-HPLC)

Actions biochimiques/physiologiques

Salicylic acid (SA) delivers local and systemic acquired resistance (LAR and SAR) against various diseases in plants. It acts as a secondary metabolite and regulate various physiological processes such as respiration, stomatal closure and senescence-associated gene expression. In addition, SA also controls abiotic stress, basal thermotolerance, nodulation in legumes and fruit yield. It plays a vital role in modulation of flowering and thermogenesis (heat production) in plants. SA together with reactive oxygen species (ROS) and nitric oxide (NO) triggers cell death in plants.

Informations sur la sécurité

• Pictogrammes: GHS08,GHS05,GHS07
• Mention d'avertissement: Danger
• Mentions de danger: H302,H318,H361d
• Conseils de prudence: P202 - P264 - P280 - P301 + P312 - P305 + P351 + P338 - P308 + P313
• Classification des risques: Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 2
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): 314.6 °F - closed cup
• Point d'éclair (°C): 157 °C - closed cup
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves