03557
Poly(éthylène glycol)
tested according to Ph. Eur., 35,000
Synonyme(s) :
PEG
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About This Item
Formule linéaire :
H(OCH2CH2)nOH
Numéro CAS:
Numéro MDL:
Code UNSPSC :
12161900
ID de substance PubChem :
Nomenclature NACRES :
NA.21
Produits recommandés
Agence
tested according to Ph. Eur.
Niveau de qualité
Forme
powder
Poids mol.
~35000
Solubilité
aliphatic hydrocarbons: slightly soluble
organic solvents: soluble
Application(s)
pharmaceutical (small molecule)
Chaîne SMILES
C(CO)O
InChI
1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
Clé InChI
LYCAIKOWRPUZTN-UHFFFAOYSA-N
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Application
Poly (ethylene glycol) can be used as a test compound utilized in the overproduction and purification of recombinant Lactobacillus reuteri LrNDT. It can also be used for concentrating the mutants with lower secretion levels used in ELISAs for the quantitation of shgp190 and of the LIF/shgp190 complexes.
Actions biochimiques/physiologiques
Polyethylene glycol (PEG) is a condensation polymer of ethylene oxide and water. It enhances the refolding of extracted proteins. This enables characterization of crystallized proteins.
Notes préparatoires
Poly(ethylene glycol) dissolves in many organic solvents and is readily soluble in aromatic hydrocarbons. It also slightly dissolves in aliphatic hydrocarbons.
Code de la classe de stockage
10 - Combustible liquids
Classe de danger pour l'eau (WGK)
WGK 1
Point d'éclair (°F)
281.5 °F - closed cup
Point d'éclair (°C)
138.6 °C - closed cup
Équipement de protection individuelle
Eyeshields, Gloves, type N95 (US)
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Les clients ont également consulté
Jesús Fernández-Lucas et al.
Applied and environmental microbiology, 76(5), 1462-1470 (2010-01-06)
A novel type II nucleoside 2'-deoxyribosyltransferase from Lactobacillus reuteri (LrNDT) has been cloned and overexpressed in Escherichia coli. The recombinant LrNDT has been structural and functionally characterized. Sedimentation equilibrium analysis revealed a homohexameric molecule of 114 kDa. Circular dichroism studies
Juliette Bitard et al.
The Journal of biological chemistry, 278(18), 16253-16261 (2003-02-26)
The leukemia inhibitory factor (LIF) receptor comprises the low affinity binding chain gp190 and the high affinity converter gp130. The ectodomain of gp190 is among the most complex in the hematopoietin receptor family, because it contains two typical cytokine receptor
J L Cleland et al.
The Journal of biological chemistry, 267(19), 13327-13334 (1992-07-05)
Polyethylene glycol (PEG) inhibited aggregation during refolding of bovine carbonic anhydrase B (CAB) through the formation of a nonassociating PEG-intermediate complex. Stoichiometric concentrations of PEG were required for complete recovery of active protein during refolding at aggregating conditions. For example
J L Cleland et al.
Bio/technology (Nature Publishing Company), 10(9), 1013-1019 (1992-09-01)
Previous studies on the refolding of recombinant bovine carbonic anhydrase B (CAB) indicated that polyethylene glycol (PEG) significantly enhanced the recovery of active protein by reducing aggregation. To further test the ability of PEG to enhance refolding, three recombinant human
I L Konorova et al.
Patologicheskaia fiziologiia i eksperimental'naia terapiia, (4)(4), 7-9 (1991-07-01)
The search for antiaggregatory compounds is undertaken, as a rule, under in vitro conditions which do not reflect the dynamics of the real process. The present work deals with study of the peculiarities of the development of the collagen induced
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