MABD120
Anti-FGFR4 Antibody, clone 4H2B10B2
ascites fluid, clone 4H2B10B2, from mouse
Synonyme(s) :
Fibroblast growth factor receptor
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About This Item
Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41
Produits recommandés
Source biologique
mouse
Niveau de qualité
Forme d'anticorps
ascites fluid
Type de produit anticorps
primary antibodies
Clone
4H2B10B2, monoclonal
Espèces réactives
human
Technique(s)
immunohistochemistry: suitable
western blot: suitable
Isotype
IgG1
Numéro d'accès UniProt
Conditions d'expédition
wet ice
Modification post-traductionnelle de la cible
unmodified
Informations sur le gène
human ... FGFR4(2264)
Description générale
FGFR4 (fibroblast growth factor receptor 4) is part of a family of fibroblast growth factor receptors that plays an important role in the biological functions of specific growth factors. The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. There are four members of the FGF receptor family: FGFR-1 (flg), FGFR-2 (bek, KGFR), FGFR-3 and FGFR-4. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation.
The previously assigned protein identifier G3JVM2 has been merged into P22455. Full details can be found on the UniProt database.
The previously assigned protein identifier G3JVM2 has been merged into P22455. Full details can be found on the UniProt database.
Immunogène
Purified recombinant fragment of human FGFR4 expressed in E. Coli.
Application
Detect FGFR4 using this mouse monoclonal antibody, Anti-FGFR4 Antibody, clone 4H2B10B2 validated for use in western blotting & IHC.
Immunohistochemistry Analysis: A 1:200-1,000 dilution from a representative lot detected FGFR4 in human liver tissue.
Optimal working dilutions must be determined by end user.
Optimal working dilutions must be determined by end user.
Research Category
Stem Cell Research
Stem Cell Research
Research Sub Category
Pluripotent & Early Differentiation
Pluripotent & Early Differentiation
Qualité
Evaluated by Western Blotting in HEK293T cells transfected with the pCMV6-ENTRY control and pCMV6-ENTRY FGFR4 cDNA .
Western Blotting Analysis: A 1:500-2,000 dilution of this antibody detected FGFR4 in HEK293T cells transfected with pCMV6-ENTRY FGFR4 cDNA.
Western Blotting Analysis: A 1:500-2,000 dilution of this antibody detected FGFR4 in HEK293T cells transfected with pCMV6-ENTRY FGFR4 cDNA.
Description de la cible
~88 kDa observed
Forme physique
Mouse monoclonal IgG1 ascitic fluid containing up to 0.1% sodium azide.
Unpurified
Stockage et stabilité
Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Remarque sur l'analyse
Control
HEK293T cells transfected with the pCMV6-ENTRY control and pCMV6-ENTRY FGFR4 cDNA
HEK293T cells transfected with the pCMV6-ENTRY control and pCMV6-ENTRY FGFR4 cDNA
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Code de la classe de stockage
12 - Non Combustible Liquids
Classe de danger pour l'eau (WGK)
nwg
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Certificats d'analyse (COA)
Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".
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