MAB4356C3

Anti-DPPA-2 Antibody, clone 6C1.2, Cy3 conjugate

clone 6C1.2, from mouse, CY3 conjugate

• Synonyme(s) : Pluripotent embryonic stem cell-related gene 1 protein, developmental pluripotency associated 2
• Code UNSPSC : 12352203
• eCl@ss : 32160702
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: mouse
• Niveau de qualité: 100
• Conjugué: CY3 conjugate
• Forme d'anticorps: purified immunoglobulin
• Type de produit anticorps: primary antibodies
• Clone: 6C1.2, monoclonal
• Espèces réactives: mouse
• Technique(s): immunocytochemistry: suitable
• Isotype: IgG2a
• Numéro d'accès NCBI: NP_082891
• Numéro d'accès UniProt: Q9CWH0
• Conditions d'expédition: wet ice
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: mouse ... Dppa2(73703)

Description

Description générale

DPPA-2 (developmental pluripotency associated-2) is a novel Oct-4-related protein that is localized to the nucleus of mouse fetal germ cells. DPPA-2 has binding sites for both POU and Sox-2 protein domains and is expressed primarily in the developing germ line following gastrulation. These associations suggest that this protein participates in a very strong supportive role in maintaining cell pluripotentiality. In addition to its role as a pluripotency marker, more recent research using cancer cells suggests that DPPA-2 may also act as an embryo-cancer antigen—pointing to the presence of abnormal cell growth and the formation of cancerous cells.

Immunogène

recombinant protein corresponding to mouse DPPA-2.

Application

Detect DPPA-2 using this Anti-DPPA-2 Antibody, clone 6C1.2, Cy3 conjugate validated for use in ICC.

Research Category
Stem Cell Research

Research Sub Category
Pluripotent & Early Differentiation

Qualité

Evaluated by Immunocytochemistry in Mouse Embryonic Stem Cells (SCR012). Immunocytochemsitry Analysis: A 1:100 dilution of this antibody detected DPPA2 in Mouse Embryonic Stem Cells (SCR012).

Description de la cible

~30 kDa observed

Forme physique

Protein G Purified

Purified mouse monoclonal IgG2aλ supernatant in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stockage et stabilité

Maintain refrigerated at 2-8ºC protected from light in undiluted aliquots for up to 6 months from date of receipt.

Remarque sur l'analyse

Control
Mouse Embryonic Stem Cells (SCR012).

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 2