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MAB2146

Sigma-Aldrich

Anti-ICAM-1 Antibody, clone P2A4

clone P2A4, Chemicon®, from mouse

Synonyme(s) :

CD54

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

mouse

Niveau de qualité

Forme d'anticorps

purified antibody

Type de produit anticorps

primary antibodies

Clone

P2A4, monoclonal

Espèces réactives

human

Fabricant/nom de marque

Chemicon®

Technique(s)

ELISA: suitable
flow cytometry: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable

Isotype

IgG1

Numéro d'accès NCBI

Numéro d'accès UniProt

Conditions d'expédition

wet ice

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... ICAM1(3383)

Spécificité

Human ICAM-1

Immunogène

IL-1beta activated HUVEC (human)

Application

Anti-ICAM-1 Antibody, clone P2A4 is an antibody against ICAM-1 for use in ELISA, FC, IP, IC, IH.
Immunohistochemistry: for use on acetone or paraformaldehyde fixed tissue

Immunocytochemistry: for use on B cells, PBL, T cells

Immunoprecipitation

FACS

ELISA

Inhibits ICAM-1 dependent adhesive interactions

Optimal working dilutions must be determined by end user.
Research Category
Cell Structure
Research Sub Category
Adhesion (CAMs)

Forme physique

Format: Purified
Nonsterile liquid contains 0.2M phosphate buffer, 0.25M sodium chloride, and 0.1% sodium azide. Filtered through a 0.45 micron membrane filter.

Stockage et stabilité

Maintain at +2-8°C.

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informations légales

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Alba Carmona et al.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 19(10), 1439-1445 (2013-07-13)
Endothelial dysfunction seems to be a key factor in the development of several complications observed early after hematopoietic stem cell transplantation (HSCT). The conditioning regimen and many other factors associated with the procedure are responsible for this endothelial damage. The
João M Furtado et al.
Immunology and cell biology, 90(9), 912-915 (2012-04-25)
Retinal infection is the most common clinical manifestation of toxoplasmosis. The route by which circulating Toxoplasma gondii tachyzoites cross the vascular endothelium to enter the human retina is unknown. Convincing studies using murine encephalitis models have strongly implicated leukocyte taxis
Akio Kawakami et al.
Circulation, 114(7), 681-687 (2006-08-09)
Activation of vascular endothelial cells (ECs) plays an important role in atherogenesis and plaque instability. Lipoproteins containing apolipoprotein CIII (apoCIII) predict coronary heart disease (CHD). We recently reported that apoCIII has a proinflammatory effect on human monocytes. In this study
Qiangjun Cai et al.
Arteriosclerosis, thrombosis, and vascular biology, 24(12), 2263-2270 (2004-10-02)
Vascular smooth muscle cells (VSMCs) may regulate monocyte functions within atherosclerotic lesions. We investigated the impact of VSMC/monocyte interactions on monocyte apoptosis and scavenger receptor CD36 expression, key events related to monocyte survival and differentiation. Serum deprivation significantly increased THP-1
I Lopez-Vilchez et al.
Translational psychiatry, 6(9), e886-e886 (2016-09-07)
There is a link between depression, cardiovascular events and inflammation. We have explored this connection through endothelial dysfunction, using in vivo and in vitro approaches. We evaluated circulating biomarkers of endothelial dysfunction in patients with major depression at their diagnosis

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