CBL52
Anti-Insulin-like Growth Factor-I Antibody, clone M23
clone M23, Chemicon®, from mouse
Synonyme(s) :
IGF-I
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About This Item
Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41
Produits recommandés
Source biologique
mouse
Niveau de qualité
100
300
Forme d'anticorps
affinity purified immunoglobulin
Type de produit anticorps
primary antibodies
Clone
M23, monoclonal
Espèces réactives
human
Fabricant/nom de marque
Chemicon®
Technique(s)
immunohistochemistry: suitable (paraffin)
Isotype
IgG1
Numéro d'accès NCBI
Numéro d'accès UniProt
Conditions d'expédition
wet ice
Informations sur le gène
human ... IGF1(3479)
Spécificité
The basic IGF-1-like forms (pl>9.0) showed substantial cross-reactivity, as did rat and mouse sera. Monoclonal antibody BM23 was capable of abolishing the biological activities of IGF-1 in vitro bioassays for insulin-like, mitogenic and sulphation activities.
AFFINITY CONSTANT: The affinity of monoclonal antibody BM23 for IGF-1 was 1 x 10E10 L/mole and the cross reactivities of IGF-2, MSA and porcine insulin were 1%, 0.05% and 0.0001% respectively
AFFINITY CONSTANT: The affinity of monoclonal antibody BM23 for IGF-1 was 1 x 10E10 L/mole and the cross reactivities of IGF-2, MSA and porcine insulin were 1%, 0.05% and 0.0001% respectively
Immunogène
Purified human IGF-1.
Application
Immunohistological staining of tissue sections on frozen or formalin fixed paraffin wax embedded sections
Optimal working dilutions must be determined by the end user.
Optimal working dilutions must be determined by the end user.
Research Category
Signaling
Signaling
Research Sub Category
Insulin/Energy Signaling
Insulin/Energy Signaling
This Anti-Insulin-like Growth Factor-I Antibody, clone M23 is validated for use in IH(P) for the detection of Insulin-like Growth Factor-I.
Forme physique
Format: Purified
The monoclonal is presented at a concentration of 100μg/1ml in phosphate buffered saline containing 10mM sodium azide and 1mg/ml bovine serum albumin. We recommend that each laboratory determine an optimum working titre for use in its particular application.
Stockage et stabilité
For use within 1 month of purchase store at +4°C, for long term storage aliquot antibody into small volumes and store at -20°C.
Informations légales
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Code de la classe de stockage
12 - Non Combustible Liquids
Classe de danger pour l'eau (WGK)
WGK 2
Certificats d'analyse (COA)
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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.
E Maiorano et al.
Applied immunohistochemistry & molecular morphology : AIMM, 8(2), 110-119 (2000-08-11)
Insulin-like growth factor 1 (IGF-1) likely is involved in thyrocyte proliferation via autocrine mechanisms, but limited data are available on its in vivo expression in thyroid neoplasms. This prompted us to explore IGF-1 expression at the protein and mRNA levels
Ali Aslan et al.
Medical science monitor : international medical journal of experimental and clinical research, 25, 5510-5517 (2019-07-26)
BACKGROUND There is no study in the literature investigating the expression levels of WT1, p53, and IGF-1 in colon polyp subtypes. In this study, we aimed to investigate the expression levels of IGF-1, p53, and WT1 in colon polyp subtypes
An immunoenzymatic method to measure IGF-1 in milk.
A Guidi, L Castigliego, G Iannone, A Armani, D Gianfaldoni
Veterinary Research Communications null
Hakryul Jo et al.
Molecular and cellular biology, 28(13), 4285-4299 (2008-05-07)
Cancer cells in their respective microenvironments must endure various growth-constraining stresses. Under these conditions, the cancer cell-derived factors are thought to modulate the signaling pathways between cell growth and dormancy. Here, we describe a cancer cell-derived regulatory system that modulates
Y-F Huang et al.
British journal of cancer, 99(7), 1096-1102 (2008-09-11)
This study was aimed to identify the expression and the correlation of insulin-like growth factor-1 (IGF-1) system and their prognostic impacts in cervical cancer. Seventy-two patients with early-stage cervical cancer were eligible. We obtained the serum levels of total IGF-1
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