ABN160

Anti-ARMS2 Antibody

from rabbit, purified by affinity chromatography

• Synonyme(s) : Age-related maculopathy susceptibility protein 2
• Code UNSPSC : 12352203
• eCl@ss : 32160702
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Produit purifié par: affinity chromatography
• Espèces réactives: human
• Technique(s): western blot: suitable
• Numéro d'accès NCBI: NP_001093137
• Numéro d'accès UniProt: P0C7Q2
• Conditions d'expédition: wet ice
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... ARMS2(387715)

Description

Description générale

Age-related maculopathy susceptibility protein 2 (ARMS2) is highly expressed in the human placenta and retina. The biological function of ARMS2 has not been fully characterized. However, previous studies have linked mutations in the ARMS2 and HtrA1 genes, located on chromosome 10q26, to the occurrence of age-related macular degeneration type 8, a condition of irreversible vision loss in the elderly.

Immunogène

KLH-conjugated linear peptide corresponding to human ARMS2.

Application

Immunocytochemistry Analysis: A representative lot was used by an independent laboratory in ARPE-19 cells. (Pericak-Vance, M., et al. (2009). Invest Ophthalmol Vis Sci. 50(7): 3084–3090.)

Research Category
Neuroscience

Research Sub Category
Neurodegenerative Diseases

This Anti-ARMS2 Antibody is validated for use in Western Blotting for the detection of ARMS2.

Qualité

Evaluated by Western Blot in human placenta tissue lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected ARMS2 on 10 µg of human placenta tissue lysate.

Description de la cible

~12 kDa observed. An uncharacterized band appears at ~60 kDa in some lysates.

Forme physique

Affinity purified

Purified rabbit polyclonal in PBS containing 0.1% azide.

Stockage et stabilité

Stable for 1 year at 2-8°C from date of receipt.

Remarque sur l'analyse

Control
Human placenta tissue lysate

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids