ABF205

Anti-TRIM5 delta Antibody

from rabbit, purified by affinity chromatography

• Synonyme(s) : Tripartite motif-containing protein 5, RING finger protein 88
• Code UNSPSC : 12352203
• eCl@ss : 32160702
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Produit purifié par: affinity chromatography
• Espèces réactives: mouse
• Réactivité de l'espèce (prédite par homologie): human (immunogen homology)
• Technique(s): immunohistochemistry: suitable; western blot: suitable
• Numéro d'accès UniProt: Q9C035
• Conditions d'expédition: wet ice
• Modification post-traductionnelle de la cible: unmodified

Description

Description générale

Tripartite motif-containing protein 5 (TRIM5), also known as the RING finger protein 88 (RNF88), is a member of a broad family of otherwise unrelated proteins defined by the presence of a tripartite motif containing a RING domain, a B-box type 1, and a B-box type 2, followed by a coiled-coil region. TRIM5 has six alternately spliced isoforms, the longest of which is the alpha variant which also contains a carboxy-terminal B30.2 (SPRY) domain. The TRIM5 delta isoform has been shown to colocalize with BTBD1 and BTBD2 in punctate or elongated cytoplasmic bodies in several mouse and human cells serving as a scaffold for the assembly of endogenous BTBD proteins.

Immunogène

KLH-conjugated linear peptide corresponding to human TRIM5 delta.

Application

Anti-TRIM5 delta Antibody is a highly specific rabbit polyclonal antibody, that targets Tripartite motif-containing protein 5 & has been tested in western blotting & IHC.

Immunohistochemistry Analysis: 1 µg/mL from a representative lot detected TRIM5 delta in mouse brain tissue.

Research Category
Inflammation & Immunology

Research Sub Category
Immunoglobulins & Immunology

Qualité

Evaluated by Western Blotting in mouse brain tissue lysate.

Western Blotting Analysis: 2 µg/mL of this antibody detected TRIM5 delta in 15 µg of mouse brain tissue lysate.

Description de la cible

~25 kDa observed. Uniprot describes 6 isoforms ranging between ~30 kDa and ~56 kDa

Forme physique

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Stockage et stabilité

Stable for 1 year at 2-8°C from date of receipt.

Remarque sur l'analyse

Control
Mouse brain tissue lysate

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable