ABE604

Anti-Bonzo Antibody

from rabbit, purified by affinity chromatography

• Synonyme(s) : C-X-C chemokine receptor type 6, CXC-R6, CXCR-6, CDw186, G-protein coupled receptor STRL33, G-protein coupled receptor bonzo, CD186, BONZO, STRL33, TYMSTR
• Code UNSPSC : 12352203
• eCl@ss : 32160702
• Nomenclature NACRES : NA.41
• Clone: polyclonal
• application: IHC; WB
• Espèces réactives: human
• Technique(s): immunohistochemistry: suitable; western blot: suitable

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Produit purifié par: affinity chromatography
• Espèces réactives: human
• Technique(s): immunohistochemistry: suitable; western blot: suitable
• Numéro d'accès UniProt: O00574
• Conditions d'expédition: wet ice
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... CXCR6(10663)

Description

Description générale

G-protein coupled receptor bonzo (BONZO), also known as C-X-C chemokine receptor type 6 (CXCR6,CXC-R6,CXCR-6), CDw186 (CD186), G-protein coupled receptor STRL33 (STRL33), and TYMSTR, is a receptor for the C-X-C chemokine CXCL16 and is shown to be used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1. Certain G protein-coupled receptors including CCR5, CXCR4, CCR3, and CCR2b have been identified as HIV coreceptors. BONZO is expressed in lymphoid tissues and activated T cells.

Spécificité

This antibody recognizes the N-terminus of Bonzo.

Immunogène

KLH-conjugated linear peptide corresponding to the N-terminus of human Bonzo.

Application

Detect CXCR6 using this rabbit polyclonal antibody, Anti-Bonzo Antibody validated for use in western blotting & IHC.

Immunohistochemistry Analysis: 20 µg/mL from a representative lot detected Bonzo in human spleen tissue.

Qualité

Evaluated by Western Blotting/Peptide Inhibition Assay in human spleen tissue lysate.

Western Blotting/Peptide Inhibition Assay Analysis: 1 µg/mL of this antibody detected Bonzo in 15 µg of human spleen tissue lysate.

Description de la cible

~45 kDa observed. Uncharacterized bands may appear in some lysate(s).

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable