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ABC845

Sigma-Aldrich

Anti-Nop30 Antibody

from rabbit, purified by affinity chromatography

Synonyme(s) :

Nucleolar protein 3, Apoptosis repressor with CARD, Muscle-enriched cytoplasmic protein, Myp, Nucleolar protein of 30 kDa, Nop30

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

primary antibodies

Clone

polyclonal

Produit purifié par

affinity chromatography

Espèces réactives

mouse

Technique(s)

western blot: suitable

Numéro d'accès UniProt

O60936

Conditions d'expédition

wet ice

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... NOL3(8996)

Description générale

Apoptosis, also known as programmed cell death, plays major roles in development and normal tissue turnover in addition to tumor formation. Nop30 (also known as Nucleolar protein 3, Apoptosis repressor with CARD, Muscle-enriched cytoplasmic protein, Myp, Nucleolar protein of 30 kDa, and Nop30) is an alternate splicing isoform of ARC. While ARC interacts with caspase-2 and –8 and suppresses apoptosis induced by cell death adapters FADD and TRADD and by cell death receptors Fas, TNFR-1 and DR3, Nop30 multimerizes and binds to the splicing factor SRp30c and may act to influence alternative splice site selection in vivo.

Spécificité

This Nop30 antibody will not detect ARC protein.

Immunogène

Epitope: C-terminus
KLH-conjugated linear peptide corresponding to a 14 amino acid peptide near the C-terminus of human Nop30.

Application

Anti-Nop30 Antibody is a highly specific rabbit polyclonal antibody, that targets Nucleolar protein 3 & has been tested in western blotting.
Research Category
Apoptosis & Cancer
Research Sub Category
Apoptosis - Additional

Qualité

Evaluated by Western Blotting in mouse muscle tissue lysate.

Western Blotting Analysis: 2 μg/mL of this antibody detected Nop30 in mouse muscle tissue lysate.

Description de la cible

~24 kDa observed. Uncharacterized bands may be observed in some lysate(s).

Forme physique

Antigen Affinity Purified
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Stockage et stabilité

Stable for 1 year at 2-8°C from date of receipt.

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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