ABC152

Anti-Annexin A2 Antibody

from rabbit, purified by affinity chromatography

• Synonyme(s) : Annexin A2, Annexin II, Annexin-2, Calpactin I heavy chain, Calpactin-1 heavy chain, Chromobindin-8, Lipocortin II, Placental anticoagulant protein IV, PAP-IV, Protein I, p36
• Code UNSPSC : 12352203
• eCl@ss : 32160702
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Forme d'anticorps: purified antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Produit purifié par: affinity chromatography
• Espèces réactives: rat, human
• Réactivité de l'espèce (prédite par homologie): primate (based on 100% sequence homology), mouse (based on 100% sequence homology), bovine (based on 100% sequence homology), porcine (based on 100% sequence homology), canine (based on 100% sequence homology)
• Technique(s): immunohistochemistry: suitable (paraffin); western blot: suitable
• Numéro d'accès NCBI: NP_004030
• Numéro d'accès UniProt: P07355
• Conditions d'expédition: wet ice
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... ANXA2(302)

Description

Description générale

Annexin A2 is known by several other names including: Annexin II, Calpactin I heavy chain, Chromobindin-8, Lipocortin II and Placental anticoagulant protein IV. Annexin A2 is a calcium-regulated membrane-binding protein that binds two calcium ions with high affinity. Annexin A2′s affinity for calcium is enhanced by anionic phospholipids. Annexin A2 has been shown to bind to human cytomegalvirus (HCMV) and may be involved in heat-stress response and apoptosis.

Spécificité

This antibody recognizes the Annexin 1 repeat domain of Annexin A2.

Immunogène

Epitope: Annexin 1 repeat domain

KLH-conjugated linear peptide corresponding to Annexin 1 repeat domain of human Annexin A2.

Application

Anti-Annexin A2 is an antibody targeting the Annexin A2 protein, validated for use in WB & IHC.

Immunohistochemistry Analysis: A 1:500 dilution from a representative lot detected Annexin A2 in human and rat colon tissues.

Research Category
Apoptosis & Cancer

Research Sub Category
Apoptosis - Additional

Qualité

Evaluated by Western Blotting in A549 cell lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected Annexin A2 in 10 µg of A549 cell lysate.

Description de la cible

~36 kDa observed

Forme physique

Protein A purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stockage et stabilité

Stable for 1 year at 2-8°C from date of receipt.

Remarque sur l'analyse

Control
A549 cell lysate

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable