Striatin is found in all mammalian cells and may be involved in vesicular transport, dendrite growth and cellular signalling. It binds Protein phosphatase 2A (PP2A) A and C subunits and calmodulin and appears to modulate PP2A activity. It also binds the human homolog of the yeast protein, Mob1, which has been implicated in mitotic progression in yeast. It is a member of a family of proteins that also include SG2NA (striatin 3) and Zinedin (striatin 4).
Spécificité
Reacts with Striatin. No cross reactivity with SG2NA.
Immunogène
Synthetic Striatin peptide.
Application
Anti-Striatin Antibody detects level of Striatin & has been published & validated for use in IP, WB & IC.
Research Category Neuroscience
Research Sub Category Synapse & Synaptic Biology
Western blot: 1:500-1:1,000. The antibody reacts with the ~110 kDa striatin protein in 293 cell lysate.
Immunocytochemistry: 1:500
Immunoprecitation: 3 μL recommended as starting point.
Optimal working dilutions must be determined by the end user.
Forme physique
Rabbit serum. Liquid containing 40% glycerol and 0.02% sodium azide.
Stockage et stabilité
Maintain at -20°C in undiluted for up to 12 months after date of receipt. For long-term storage, may be stored at -80°C. Avoid repeated freeze/thaw cycles at temperatures below -20°C.
Informations légales
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 1
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
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Abdominal aortic aneurysms (AAAs) occur predominately in males. However, AAAs in females have rapid growth rates and rupture at smaller sizes. Mechanisms contributing to AAA progression in females are undefined. We defined effects of ovariectomy, with and without 17-β estradiol
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