AB5559
Anti-GABA A Receptor γ2 Antibody, cytoplasmic loop
Chemicon®, from rabbit
Synonyme(s) :
Anti-CAE2, Anti-DEE74, Anti-ECA2, Anti-EIEE74, Anti-FEB8, Anti-GEFSP3
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About This Item
Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41
Produits recommandés
Source biologique
rabbit
Niveau de qualité
Forme d'anticorps
affinity purified immunoglobulin
Type de produit anticorps
primary antibodies
Clone
polyclonal
Produit purifié par
affinity chromatography
Espèces réactives
rat
Fabricant/nom de marque
Chemicon®
Technique(s)
immunoprecipitation (IP): suitable
western blot: suitable
Numéro d'accès NCBI
Numéro d'accès UniProt
Conditions d'expédition
dry ice
Modification post-traductionnelle de la cible
unmodified
Informations sur le gène
human ... GABRG2(2566)
Spécificité
GABAA receptor gamma2 subunit. Reacts with the ~44-47kDa gamma2 subunit of the GABAA receptor in rat brain membrane fractions.
Immunogène
Epitope: cytoplasmic loop
MBP fusion protein from the cytosolic loop of rat GABAA receptor gamma2 subunit.
Application
Anti-GABA A Receptor γ2 Antibody, cytoplasmic loop detects level of GABA A Receptor γ2 & has been published & validated for use in IP & WB.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurotransmitters & Receptors
Neurotransmitters & Receptors
Western blot: 1:1,000
Immunopreciptation: The antibody will immunoprecipitate 49% of all GABAA receptors in dodecylsulfate extracts of rat forebrains (150 μL) using 15 μg of antibody.
Optimal working dilutions must be determined by the end user.
Immunopreciptation: The antibody will immunoprecipitate 49% of all GABAA receptors in dodecylsulfate extracts of rat forebrains (150 μL) using 15 μg of antibody.
Optimal working dilutions must be determined by the end user.
Forme physique
Affinity purified immunoglobulin. Liquid in 10 mM HEPES, pH 7.5, with 150 mM NaCl, 100 μg/mL BSA and 50% glycerol. Approximate concentration is 0.2 mg/mL.
Stockage et stabilité
Maintain at -20°C in undiluted for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. Do not store in a self-defrosting freezer.
Informations légales
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Code de la classe de stockage
10 - Combustible liquids
Classe de danger pour l'eau (WGK)
WGK 2
Certificats d'analyse (COA)
Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".
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Yan Li et al.
Frontiers in aging neuroscience, 9, 212-212 (2017-07-18)
A decline in cardiovascular modulation is a feature of the normal aging process and associated with cardiovascular diseases (CVDs) such as hypertension and stroke. Exercise training is known to promote cardiovascular adaptation in young animals and positive effects on motor
Ciria C Hernandez et al.
Biomolecules, 13(3) (2023-03-30)
Febrile seizures (FS) are the most common form of epilepsy in children between six months and five years of age. FS is a self-limited type of fever-related seizure. However, complicated prolonged FS can lead to complex partial epilepsy. We found
Shimian Qu et al.
Brain communications, 2(1), fcaa028-fcaa028 (2020-05-30)
The Lennox-Gastaut syndrome is a devastating early-onset epileptic encephalopathy, associated with severe behavioural abnormalities. Its pathophysiology, however, is largely unknown. A de novo mutation (c.G358A, p.D120N) in the human GABA type-A receptor β3 subunit gene (GABRB3) has been identified in
Ciria C Hernandez et al.
Biomolecules, 13(12) (2023-12-23)
Variants in the GABRB gene, which encodes the β subunit of the GABAA receptor, have been implicated in various epileptic encephalopathies and related neurodevelopmental disorders such as Dravet syndrome and Angelman syndrome. These conditions are often associated with early-onset seizures
Adam J Harrington et al.
eLife, 5 (2016-11-04)
Numerous genetic variants associated with MEF2C are linked to autism, intellectual disability (ID) and schizophrenia (SCZ) - a heterogeneous collection of neurodevelopmental disorders with unclear pathophysiology. MEF2C is highly expressed in developing cortical excitatory neurons, but its role in their
Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..
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