Anti-ATP-binding cassette Antibody, sub-family B (MDR/TAP), member 1A
serum, Chemicon®
Synonyme(s) :
ATP binding cassette transporter 1, ATP-binding cassette 1, ATP-binding cassette transporter 1, ATP-binding cassette, sub-family A (ABC1), member 1, ATP-binding cassette, sub-family A member 1, ATP-binding cassette, sub-family A, member 1, Cholesterol ef
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This protein is a member of the superfamily of ATP-binding cassette (ABC) transporters. There are seven subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The MDR/TAP subfamily are involved in multidrug resistance. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes, and celiac disease.
Immunogène
Epitope: AA N629 – W704
Recombinant
Application
Anti-ATP-binding cassette, sub-family B (MDR/TAP), member 1A detects levels of ATP-binding cassette proteins & has been published & validated for use in WB.
Research Category Metabolism
Research Sub Category Toxicology & Drug Resistance
Western Blot Analysis: A 1:5000 dilution of this lot detected baculovirus expressed recombinant ABC protein.
Qualité
Routinely evaluated by Western Blot on baculovirus expressed recombinant ABC protein.
Description de la cible
141 kDa
Forme physique
Raw rabbit serum with 0.05% sodium azide.
Stockage et stabilité
Maintain at -20°C for up to 12 months from date of receipt.
Informations légales
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Code de la classe de stockage
10 - Combustible liquids
Classe de danger pour l'eau (WGK)
WGK 1
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The multidrug-resistant phenotype of tumor cells is acquired via an increased capability of drug efflux by ABC transporters and causes serious problems in cancer treatment. With the aim to uncover whether changes induced by epigenetic mechanisms in the expression level
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