8.51069

2-Biotinyldimedone

Novabiochem^®

• Synonyme(s) : 2-Biotinyldimedone
• Formule empirique (notation de Hill) : C₁₈H₂₆N₂O₄S
• Numéro CAS: 194038-08-9
• Poids moléculaire : 366.48
• MDL number: MFCD10567141
• NACRES: NA.22
• UNSPSC Code: 12352005

Propriétés

• Quality Segment: 200
• product line: Novabiochem^®
• assay: ≥98% (TLC), ≥98.0% (HPLC)
• form: powder
• reaction suitability: reaction type: Biotinylations
• manufacturer/tradename: Novabiochem^®
• application(s): peptide synthesis
• storage temp.: 2-30°C
• InChI key: JMXONQIABZZOLX-FSBGKCOPSA-N

Description

General description

A reagent for the reversible labeling of peptides with biotin ^[1]. Labeling of the N-terminal amine of resin-bound peptides is carried out by incubating overnight with excess reagent in DMF. The biotinylated peptide is obtained following TFA cleavage. Removal of the biotin label is effected by treatment with 5% aqueous hydrazine.

Associated Protocols and Technical Articles
Purification of Peptides using Chemoselective Tags

Literature references

^[1] B. Kellam, et al. (1997) Tetrahedron Lett., 38, 5391

Analysis Note

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Purity (TLC(011A)): ≥ 98 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Other Notes

Replaces: 01-63-0108

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Classe de stockage: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable