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8.07491

Sigma-Aldrich

Poly(éthylène glycol)

6000, for synthesis

Synonyme(s) :

PEG

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175,00 €
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684,00 €
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686,00 €

81,40 €

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Sélectionner une taille de conditionnement

Changer de vue
1 KG
81,40 €
5 KG
175,00 €
50 KG
684,00 €
50 KG
686,00 €

About This Item

Formule linéaire :
H(OCH2CH2)nOH
Numéro CAS:
25322-68-3
Numéro MDL:
MFCD00081839
Code UNSPSC :
13111021
Numéro de classement CE :
500-038-2
Nomenclature NACRES :
NA.22

81,40 €

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Devis pour commande en gros

Pression de vapeur

<0.01 hPa ( 20 °C)

Niveau de qualité

200

Forme

solid

Température d'inflammation spontanée

420 °C

Puissance

28000 mg/kg LD50, oral (Rat)
>20000 mg/kg LD50, skin (Rabbit)

pH

5-7 (20 °C, 100 g/L in H2O)

Pf

58-63 °C

Température de transition

flash point 270 °C

Densité

1.2 g/cm3 at 20 °C

Température de stockage

2-30°C

Chaîne SMILES 

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

Clé InChI

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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Catégories apparentées

Description générale

Polyethylene glycol (PEG) is a synthetic, hydrophilic, biocompatible polymer that has a wide range of uses in PEGylation, surface conjugation, nanoparticle coating, and crosslinking for hydrogels, etc. PEGs are made by polymerizing ethylene oxide via a ring-opening reaction to produce a wide range of molecular weights and molecular weight distributions (polydispersity).

Application

Polyethylene glycol 6000 is a non-ionic surfactant that can be used as a structure-directing agent to prepare mesoporous γ-Al2O3. PEG 6000 induced the formation of the lamellate structure morphology of boehmite nanoparticles with improved textural properties such as high surface area, larger pore volume, and pore size.[1] It is also used in drug formulations to enhance the dissolution rate of the poorly water-soluble drug molecule.[2][3] PEG-6000 can also be used in the purification of nucleic acids via the selective precipitation method. This approach is economically cost-effective and faster than the commonly employed chromatographic purification method.[4]

Remarque sur l'analyse

Melting range (lower value): ≥ 59 °C
Melting range (upper value): ≤ 64 °C
Hydroxyl value: 16 - 23
Average molecular mass: 5000 - 7000
Identity (IR): passes test

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

281.5 °F - closed cup

Point d'éclair (°C)

138.6 °C - closed cup

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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S Biswal et al.
AAPS PharmSciTech, 9(2), 563-570 (2008-05-07)
The aim of the present study was to enhance the dissolution rate of gliclazide using its solid dispersions (SDs) with polyethylene glycol (PEG) 6000. The phase solubility behavior of gliclazide in presence of various concentrations of PEG 6000 in 0.1
A facile rout to synthesis lamellate structure mesoporous alumina using polyethylene glycol 6000 (PEG, molecular weight= 6000) as structure directing agent
Su Ai-ping, et al.
Microporous and Mesoporous Materials : The Official Journal of the International Zeolite Association, 159, 36-41 (2012)
Purification of nucleic acids by selective precipitation with polyethylene glycol 6000.
Axel Schmitz et al.
Analytical biochemistry, 354(2), 311-313 (2006-05-27)
S Verheyen et al.
International journal of pharmaceutics, 249(1-2), 45-58 (2002-11-16)
Solid dispersion literature, describing the mechanism of dissolution of drug-polyethylene glycol dispersions, still shows some gaps; (A). only few studies include experiments evaluating solid solution formation and the particle size of the drug in the dispersion particles, two factors that

Questions

1–3 sur 3 questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 réponse

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 réponse

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  3. Is it possible to use the product Polyethylene glycol 6000 (8074911000) to soften seed coats to aid in germination?

    1 réponse

    1. The information from Jelitto Perennial Seeds suggests that for hard-shelled seeds, mechanical damaging of the shell or treatment with a softener such as Polyethylene glycol 6000 (PEG 6000) can be helpful for quicker swelling. However, there is no specific mention of product number 807491 in particular for this purpose.

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