581004

Telomerase Inhibitor III, Sodium Salt

The Telomerase Inhibitor III, Sodium Salt controls the biological activity of Telomerase. This small molecule/inhibitor is primarily used for Cell Structure applications.

• Synonyme(s) : TAG-6, 5ʹ-d(TTAGGG)-3ʹ
• Code UNSPSC : 12352200

Propriétés

• Niveau de qualité: 100
• Forme: lyophilized
• Fabricant/nom de marque: Calbiochem^®
• Conditions de stockage: OK to freeze; desiccated (hygroscopic); protect from light
• Solubilité: water: soluble
• Conditions d'expédition: wet ice
• Température de stockage: −70°C

Description

Description générale

A short, cell-permeable hexameric phosphorothioate oligonucleotide (PS-ODN) telomer mimic that inhibits telomerase activity in cell lysates and lengthens cell doubling time in vitro and in vivo at concentrations of less than 2.5 µM.

A short, cell-permeable hexameric phosphorothioate oligonucleotide (PS-ODN) telomere mimic that inhibits telomerase activity in cell lysates and lengthens cell doubling time in vitro and in vivo at concentrations of less than 2.5 µM. Note: 150 nmol = 285 µg.

M.W. ~1900.

Actions biochimiques/physiologiques

Cell permeable: yes

Primary Target
Telomerase activity in cell lysates

Product competes with ATP.

Reversible: no

Conditionnement

Packaged under inert gas

Avertissement

Toxicity: Harmful & Carcinogenic / Teratogenic (E)

Séquence

5′-d(TTAGGG)-3′

Autres remarques

Mata, J.E., et al. 1997. Toxicol. Appl. Pharmacol. 144, 189.

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable