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219007

Sigma-Aldrich

Caspase Inhibitor VI

Z-VAD-FMK, CAS 161401-82-7, is an irreversible pan caspase inhibitor. Does not require pretreatment with esterase for in vitro studies.

Synonyme(s) :

Caspase Inhibitor VI, Z-VAD-FMK

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About This Item

Formule empirique (notation de Hill):
C21H28FN3O7
Numéro CAS:
Poids moléculaire :
453.46
Code UNSPSC :
12352200
Nomenclature NACRES :
NA.54

Niveau de qualité

Pureté

≥98% (HPLC)

Forme

solid

Fabricant/nom de marque

Calbiochem®

Conditions de stockage

OK to freeze
desiccated

Couleur

off-white

Solubilité

DMSO: 9 mg/mL

Conditions d'expédition

ambient

Température de stockage

−20°C

InChI

1S/C21H28FN3O7/c1-12(2)18(25-21(31)32-11-14-7-5-4-6-8-14)20(30)23-13(3)19(29)24-15(9-17(27)28)16(26)10-22/h4-8,12-13,15,18H,9-11H2,1-3H3,(H,23,30)(H,24,29)(H,25,31)(H,27,28)/t13-,15-,18-/m0/s1

Clé InChI

SUUHZYLYARUNIA-YEWWUXTCSA-N

Description générale

An irreversible general caspase inhibitor. Useful for studies involving recombinant, isolated, and purified caspase enzymes. Unlike Caspase Inhibitor I (Cat. No. 627610), this inhibitor does not require pretreatment with esterase for in vitro studies. A 10 mM (1 mg/221 µl) solution of Caspase Inhibitor VI (Cat. No. 219011) in DMSO is also available.

Actions biochimiques/physiologiques

Cell permeable: no
Product does not compete with ATP.
Reversible: no

Avertissement

Toxicity: Standard Handling (A)

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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