1.04239

Glutaraldéhyde solution

for electron microscopy

• Synonyme(s) : Dialdéhyde glutarique solution, Pentane-1,5-dial
• Formule linéaire : OHC(CH₂)₃CHO
• Numéro CAS: 111-30-8
• Poids moléculaire : 100.12
• Numéro Beilstein : 605390
• Numéro MDL: MFCD00007025
• Code UNSPSC : 12352114
• Nomenclature NACRES : NA.21

Propriétés

• Pression de vapeur: 0.27 hPa ( 20 °C)
• Niveau de qualité: 200
• Forme: liquid
• Concentration: 23.5-26.5% (alkalimetric)
• Technique(s): electron microscopy: suitable
• Couleur: colorless
• pH: >3.0 (20 °C in H₂O)
• Point d'ébullition: 100.5 °C/1013 hPa
• Pf: -6 °C
• Densité: 1.06 g/cm³ at 20 °C
• Application(s): diagnostic assay manufacturing; hematology; histology
• Température de stockage: 2-8°C
• Chaîne SMILES: [H]C(CCCC([H])=O)=O
• InChI: 1S/C5H8O2/c6-4-2-1-3-5-7/h4-5H,1-3H2
• Clé InChI: SXRSQZLOMIGNAQ-UHFFFAOYSA-N

Description

Description générale

Glutardialdehyde solution 25% - for electron microscopy, is a fixing agent for specimens destined for morphological and enzyme histochemical analysis. The 25% Glutardialdehyde solution is used for the fixation of specimen of human origin for semi-thin cuttings and electron microscopy. It is diluted with phosphate buffer(Potassium dihydrogen phosphate for analysis EMSURE^® ISO (Product number 1.04873) or di-Sodium hydrogen phosphate anhydrous for analysis EMSURE^® ACS,Reag. Ph Eur (Product number 1.06586)
to achieve the corresponding working concentration. Alternatively, especially sensitive material used for enzyme histochemistry, will be fixed with glutardialdehyde according to P.J. Anderson, purified and filled into ampoules under nitrogen (Product number 1.12179). Sensitive enzymes e.g. endogenous peroxidase can often only be visualized in this way. It is an IVD registered product and CE certified, thus can be used for clinical diagnostic purposes. For more details, please see instructions for use (IFU). The IFU can be downloaded from this webpage.

Remarque sur l'analyse

Assay (alkalimetric): 23.5 - 26.5 %
pH-value: ≥ 3.0
Density (d 20 °C/ 4 °C): 1.060 - 1.065
Absorbance A (235 nm; 1:200 deluted with water; 1 cm): ≤ 0.3

Informations légales

EMSURE is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Pictogrammes: GHS05,GHS07,GHS08,GHS09
• Mention d'avertissement: Danger
• Mentions de danger: H302 + H332 - H314 - H317 - H334 - H335 - H410
• Conseils de prudence: P273 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Classification des risques: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 3
• Organes cibles: Respiratory system
• Risques supp: EUH071
• Code de la classe de stockage: 8A - Combustible, corrosive hazardous materials
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable