07-1407

Anti-GLUT-8 Antibody, CT

from rabbit

• Synonyme(s) : Glucose transporter type 8, Glucose transporter type X1, glucose transporter X1, solute carrier family 2 (facilitated glucose transporter) ; ; member 8, solute carrier family 2 (facilitated glucose transporter), ; ; member 8
• Code UNSPSC : 12352203
• eCl@ss : 32160702
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Espèces réactives: human
• Réactivité de l'espèce (prédite par homologie): mouse
• Technique(s): immunohistochemistry: suitable (paraffin)
• Numéro d'accès UniProt: Q9NY64
• Conditions d'expédition: wet ice
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... SLC2A8(29988) ; mouse ... Slc2A8(56017)

Description

Description générale

GLUT-8 is a glucose transporter facilitated by the regulation of insulin, binding cytochalasin B such that the orientation is glucose-inhibitive. In appearance, the transporter seems to be a dual-specific sugar transporter since fructose can also be inhibitive. GLUT-8 is expressed largely in the testis, where down-regulation is facilitated by estrogen. However, GLUT-8 is not highly expressed in testicular carcinoma. Lower levels of GLUT-8 are present in most other tissues.

Spécificité

Recognizes GLUT-8.

Immunogène

An 11 amino acid sequence near the C-terminus of mouse Glut-8 (Doege et al. 2000; Carayannopoulos et al. 2000)

Epitope: C-terminus

Application

Anti-GLUT-8 Antibody, C-terminus detects level of GLUT-8 & has been published & validated for use in IH(P).

Research Category
Signaling

Research Sub Category
Insulin/Energy Signaling

Qualité

Evaluated by Immunohistochemistry in human kidney tissue
Immunohistochemistry Analysis: 1:100 dilution of this lot detected GLUT-8 in human kidney tissue.

Description de la cible

Approx. 50 kDa

Liaison

Replaces: AB3140

Forme physique

Format: Purified

ImmunoAffinity Purified

Liquid in PBS with 0.1% BSA.

Stockage et stabilité

Maintain at -20°C in undiluted aliquots for up to 1 year from date of receipt. Avoid repeated freeze/thaw cycles.

Remarque sur l'analyse

Control
Human kidney tissue.

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable