06-872
Anti-IRAK Antibody
Upstate®, from rabbit
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About This Item
Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41
Source biologique
rabbit
Niveau de qualité
Forme d'anticorps
purified immunoglobulin
Type de produit anticorps
primary antibodies
Clone
polyclonal
Espèces réactives
human, mouse
Fabricant/nom de marque
Upstate®
Technique(s)
immunoprecipitation (IP): suitable
western blot: suitable
Isotype
IgG
Numéro d'accès NCBI
Numéro d'accès UniProt
Conditions d'expédition
dry ice
Modification post-traductionnelle de la cible
unmodified
Informations sur le gène
mouse ... Clec1B(56760)
Spécificité
Recognizes IRAK.
Immunogène
Peptide (DRQGPEESDEFQS) corresponding to amino acids 700-712 of human IRAK
Application
Detect IRAK using this Anti-IRAK Antibody validated for use in IP & WB.
Research Category
Signaling
Signaling
Research Sub Category
Immunological Signaling
Immunological Signaling
Qualité
routinely evaluated by immunoblot on HeLa nuclear extract
Description de la cible
80 kDa
Forme physique
Ammonium sulfate precipitation and DEAE-cellulose chromatography
Format: Purified
Protein A Purified immunoglobulin in 30% glycerol, 0.07M Tris-glycine, pH 7.4, 0.105 M NaCl, 0.035% sodium azide as a preservative.
Stockage et stabilité
Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Remarque sur l'analyse
Control
Positive Antigen Control: Catalog #12-309, Hela cell nuclear extract. Add an equal volume of Laemmli reducing sample buffer to 10 μL of extract and boil for 5 minutes to reduce the preparation. Load 20 μg of reduced extract per lane for minigels.
Positive Antigen Control: Catalog #12-309, Hela cell nuclear extract. Add an equal volume of Laemmli reducing sample buffer to 10 μL of extract and boil for 5 minutes to reduce the preparation. Load 20 μg of reduced extract per lane for minigels.
Autres remarques
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Informations légales
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Code de la classe de stockage
10 - Combustible liquids
Classe de danger pour l'eau (WGK)
WGK 2
Certificats d'analyse (COA)
Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".
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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.
Characterization of interleukin-1 receptor-associated kinase in normal and endotoxin-tolerant cells.
L Li et al.
The Journal of biological chemistry, 275(30), 23340-23345 (2000-05-16)
Interleukin-1 receptor-associated kinase (IRAK), a signal transducer for interleukin-1, has also been suggested to participate in the Toll-like receptor-mediated innate immune response to bacterial endotoxin lipopolysaccharide (LPS). Using the human promonocytic THP-1 cell line, we demonstrated that the endogenous IRAK
Cigarette smoke induces CXCL8 production by human neutrophils via activation of TLR9 receptor.
Mortaz, E; Adcock, IM; Ito, K; Kraneveld, AD; Nijkamp, FP; Folkerts, G
The European Respiratory Journal null
Candida albicans triggers activation of distinct signaling pathways to establish a proinflammatory gene expression program in primary human endothelial cells.
Verena Muller, Dorothee Viemann, Marc Schmidt, Nicole Endres, Stephan Ludwig et al.
Journal of immunology (Baltimore, Md. : 1950) (1950)
M Trofimova et al.
The Journal of biological chemistry, 271(30), 17609-17612 (1996-07-26)
The NF-kappaB/c-Rel proteins are a family of evolutionarily conserved transcription factors activated during development that in the adult, mediate many processes including the immune response. A high degree of sequence similarity is shared between the NF-kappaB/c-Rel family of transcription factors
Neutrophil signaling pathways activated by bacterial DNA stimulation.
Maria E Alvarez, Juan I Fuxman Bass, Jorge R Geffner, Paula X Fernandez Calotti et al.
Journal of immunology (Baltimore, Md. : 1950) (1950)
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