N-907

Nortriptyline hydrochloride solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant^®

• Formule empirique (notation de Hill): C₁₉H₂₂ClN
• Numéro CAS: 894-71-3
• Poids moléculaire : 299.84
• Code UNSPSC : 41116107
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: certified reference material
• Niveau de qualité: 300
• Forme: liquid
• Caractéristiques: Snap-N-Spike^®/Snap-N-Shoot^®
• Conditionnement: ampule of 1 mL
• Fabricant/nom de marque: Cerilliant^®
• Concentration: 1.0 mg/mL in methanol (as free base)
• Technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• Application(s): clinical testing
• Format: single component solution
• Température de stockage: −20°C
• Chaîne SMILES: Cl.CNCC\C=C1\c2ccccc2CCc3ccccc13
• InChI: 1S/C19H21N.ClH/c1-20-14-6-11-19-17-9-4-2-7-15(17)12-13-16-8-3-5-10-18(16)19;/h2-5,7-11,20H,6,12-14H2,1H3;1H
• Clé InChI: SHAYBENGXDALFF-UHFFFAOYSA-N
• Informations sur le gène: human ... SLC6A2(6530) , SLC6A4(6532)

Description

Description générale

Nortriptyline is a second generation tricyclic antidepressant (TCA) marketed under trade names such as Sensoval, Aventyl^®, and Pamelor^® for treatment of major depression. Nortriptyline is also an active metabolite of the TCA amitriptyline. This certified Snap-N-Spike^® solution is suitable for LC/MS or GC/MS applications in clinical toxicology, forensic analysis, urine drug testing, or medication monitoring applications.

Application

• Neuropharmacological research: A study explored the effectiveness of antidepressants in combination with psychotherapy, including nortriptyline hydrochloride. This research emphasizes its role in treating mental health disorders, showcasing the compound′s importance in neuropharmacological research and its potential for further exploration in neurotransmitter studies (Alemi et al., 2024).


• Peripheral neuropathy treatment: Nortriptyline hydrochloride was evaluated for its efficacy in managing diabetic peripheral neuropathy, highlighting its therapeutic benefits beyond traditional antidepressant applications. This study underlines its utility in biochemical assays aimed at understanding its mechanism of action on neurophysiological pathways (Bragg et al., 2024).

Informations légales

Aventyl is a registered trademark of Eli Lilly and Co.

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Pamelor is a registered trademark of Mallinckrodt Inc.

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Pictogrammes: GHS02,GHS06,GHS08
• Mention d'avertissement: Danger
• Mentions de danger: H225,H301 + H311 + H331,H370
• Conseils de prudence: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Classification des risques: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Organes cibles: Eyes,Central nervous system
• Code de la classe de stockage: 3 - Flammable liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): 49.5 °F - closed cup
• Point d'éclair (°C): 9.7 °C - closed cup