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C-045

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Cannabidiol solution

Cannabidiol solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

Synonyme(s) :

CBD

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1 ML
51,40 €

51,40 €


Disponible pour expédition le22 avril 2025Détails


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1 ML
51,40 €

About This Item

Formule empirique (notation de Hill) :
C21H30O2
Numéro CAS:
Poids moléculaire :
314.46
Numéro CE :
Numéro MDL:
Code UNSPSC :
41116107
ID de substance PubChem :
Nomenclature NACRES :
NA.24

51,40 €


Disponible pour expédition le22 avril 2025Détails


Devis pour commande en gros

Qualité

certified reference material

Niveau de qualité

Forme

liquid

Caractéristiques

SNAP-N-SPIKE®, SNAP-N-SHOOT®

Conditionnement

ampule of 1 mL

Fabricant/nom de marque

Cerilliant®

Concentration

1.0 mg/mL in methanol

Technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

Application(s)

cannabis testing
cannabis testing

Format

single component solution

Température de stockage

−20°C

Chaîne SMILES 

CCCCCc1cc(O)c([C@@H]2C=C(C)CC[C@H]2C(C)=C)c(O)c1

InChI

1S/C21H30O2/c1-5-6-7-8-16-12-19(22)21(20(23)13-16)18-11-15(4)9-10-17(18)14(2)3/h11-13,17-18,22-23H,2,5-10H2,1,3-4H3/t17-,18+/m0/s1

Clé InChI

QHMBSVQNZZTUGM-ZWKOTPCHSA-N

Informations sur le gène

human ... CNR1(1268)

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Description générale

The Certified Spiking Solution® is suitable for cannabidiol testing by HPLC, GC/MS or LC-MS/MS methods in forensic analysis, clinical toxicology, urine drug testing, and Cannabis potency or impurity profiling testing applications.

Cannabidiol (CBD) is one of the important cannabinoids found in plants of the Cannabaceae family known for its non-psychoactive properties. It forms upon the decarboxylation of its precursor cannabidiolic acid in the presence of light or heat. It shows various therapeutic properties, such as antioxidative, anti-inflammatory, antimicrobial, neuroprotective, anxiolytic, and anticonvulsant.

Application

The Certified Reference Material (CRM) in solution can also be used as follows:
  • Determination of four cannabinoids from an oil matrix using reversed-phase high-performance liquid chromatography (RP-HPLC) combined with a diode array detector (DAD)
  • Development and validation of a liquid chromatography-tandem mass spectrometry (LC-MS/MS) based technique to measure cannabidiol, ∆9-tetrahydrocannabinol, and its metabolites in whole blood samples obtained from rats administered a high dose of cannabidiol
  • Simultaneous determination of cannabidiol and tetrahydrocannabinol in different hemp oil-containing products using isocratic RP-HPLC coupled with UV detection
  • Multi-analysis of hair samples for Δ9-tetrahydrocannabinol, cannabinol, and cannabidiol by liquid-liquid extraction (LLE) followed by gas chromatography-mass spectrometry based quantification
  • Ultrasound-assisted extraction of cannabidiol from three different commercial topical products followed by GC-MS based determination

Caractéristiques et avantages

  • Fully characterized under ISO/IEC 17025 and ISO 17034 accreditation
  • Accompanied with a comprehensive Certificate of Analysis (CoA) with data on stability, homogeneity, accuracy of concentration, uncertainty, and traceability
  • Rigorously tested through real-time stability studies to ensure accuracy and shelf life
  • Gravimetrically prepared using qualified precision balances to ensure minimal uncertainty
  • Flame sealed under argon into ampoules for long-term shelf life
  • Offered in a convenient, DEA-exempt format to improve laboratory efficiency

Informations légales

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

Pictogrammes

FlameSkull and crossbonesHealth hazard

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Organes cibles

Eyes,Central nervous system

Code de la classe de stockage

3 - Flammable liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

49.5 °F - closed cup

Point d'éclair (°C)

9.7 °C - closed cup


Listes réglementaires

Les listes réglementaires sont principalement fournies pour les produits chimiques. Seules des informations limitées peuvent être fournies ici pour les produits non chimiques. L'absence d'indication signifie qu'aucun des composants n'est répertorié. Il incombe à l'utilisateur de s'assurer de l'utilisation sûre et légale du produit.

EU REACH Annex XVII (Restriction List)

CAS No.

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Certificats d'analyse (COA)

Lot/Batch Number

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Consulter la Bibliothèque de documents

R B Laprairie et al.
British journal of pharmacology, 172(20), 4790-4805 (2015-07-29)
Cannabidiol has been reported to act as an antagonist at cannabinoid CB1 receptors. We hypothesized that cannabidiol would inhibit cannabinoid agonist activity through negative allosteric modulation of CB1 receptors. Internalization of CB1 receptors, arrestin2 recruitment, and PLCβ3 and ERK1/2 phosphorylation
Raymond J M Niesink et al.
Addiction (Abingdon, England), 110(12), 1941-1950 (2015-08-04)
Between 2000 and 2005 the average percentage of Δ(9) -tetrahydrocannabinol (THC) in marijuana as sold in Dutch coffeeshops has increased substantially; the potency of domestic products (Nederwiet and Nederhasj) has particularly increased. In contrast with imported marijuana, Nederwiet hardly contained
Antonio Waldo Zuardi et al.
Current pharmaceutical design, 18(32), 5131-5140 (2012-06-22)
Δ(9)-tetrahydrocannabinol (Δ(9)-THC) is the main compound of the Cannabis Sativa responsible for most of the effects of the plant. Another major constituent is cannabidiol (CBD), formerly regarded to be devoid of pharmacological activity. However, laboratory rodents and human studies have
Alline Cristina Campos et al.
Psychopharmacology, 226(1), 13-24 (2012-09-26)
Cannabidiol (CBD) is a non-psychotomimetic constituent of Cannabis sativa plant that promotes antianxiety and anti-panic effects in animal models after acute systemic or intra-dorsal periaqueductal gray (DPAG) administration. However, the effects of CBD repeated administration, and the possible mechanisms involved
Antonio Waldo Zuardi
Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999), 30(3), 271-280 (2008-10-04)
The aim of this review is to describe the historical development of research on cannabidiol. This review was carried out on reports drawn from Medline, Web of Science and SciELO. After the elucidation of the chemical structure of cannabidiol in

Articles

HPLC separates vitamin E acetate, THC, and CBD in vape products, providing accurate analysis of commercially available vape liquids.

ISO-certified cannabinoid CRMs, THC and THCA, available as single components or mixes, for accurate potency testing.

HPLC-DAD workflow analyzes 14 cannabinoids in hemp extracts in 10 minutes using Chromolith columns for robust performance.

A complete workflow for the HPLC separation of 17 cannabinoids in different cannabis products using Ascentis® Express C18 Column in a shorter run time with retention time stability. Learn more here.

Afficher tout

Protocoles

HPLC-UV analysis of active compounds in marijuana-infused edibles for potency testing; complex matrix requires precise methods.

Rapid potency testing of marijuana-infused edibles using LC/MS on a biphenyl stationary phase detected eleven cannabinoids.

Questions

1–2 sur 2 questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 réponse
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 réponse
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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