860818P

17:0(2S-OH) Ceramide

Avanti Research^™ - A Croda Brand 860818P, powder

• Synonyme(s) : N-(2′-(S)-hydroxyheptadecanoyl)-D-erythro-sphingosine
• Formule empirique (notation de Hill): C₃₅H₆₉NO₄
• Numéro CAS: 1246298-47-4
• Poids moléculaire : 567.93
• Numéro MDL: MFCD22416674
• Code UNSPSC : 12352211
• Nomenclature NACRES : NA.25

Propriétés

• Forme: powder
• Conditionnement: pkg of 1 × 5 mg (860818P-5mg)
• Fabricant/nom de marque: Avanti Research^™ - A Croda Brand 860818P
• Type de lipide: sphingolipids
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• Chaîne SMILES: CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](NC([C@@H](O)CCCCCCCCCCCCCCC)=O)CO
• Clé InChI: MBKBHFOACJJHAN-GTQKJTMESA-N

Description

Description générale

Ceramides with 2-hydroxy fatty acids (hFA) group are mainly found in the epidermis.[1] 17:0(2S-OH) Ceramide is a unique ceramide containing 17C long chain base fatty acid (heptadecanoic acid)-with 2′-hydroxyl group in S configuration.[2]

Actions biochimiques/physiologiques

Hydroxy fatty acids (hFA)-sphingolipids helps in cell signaling.[3] They also facilitate cell differentiation and apoptosis.[2] hFA-ceramides in epidermis helps in permeability barrier function. hFA-ceramides are synthesized by fatty acid 2-hydroxylase (FA2H). Mutations of FA2H leads to the development of neurological disorders such as leukodystrophy and spastic paraparesis in humans.[3] hFA-ceramides in the cell membrane are essential for PM02734 drug to exhibit its anti-tumor activity.[4]

Conditionnement

5 mL Amber Glass Screw Cap Vial (860818P-5mg)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3