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850154P

Avanti

18:1 PI(3,5)P2

1,2-dioleoyl-sn-glycero-3-phospho-(1′-myo-inositol-3′,5′-bisphosphate) (ammonium salt), powder

Synonyme(s) :

1,2-di-(9Z-octadecenoyl)-sn-glycero-3-[phosphoinositol-3,5-bisphosphate] (ammonium salt); PIP2[3′,5′](18:1(9Z)/18:1(9Z))

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About This Item

Formule empirique (notation de Hill):
C45H94N3O19P3
Numéro CAS:
Poids moléculaire :
1074.16
Code UNSPSC :
51191904
Nomenclature NACRES :
NA.25

Pureté

>99% (TLC)

Forme

powder

Conditionnement

pkg of 1 × 100 μg (with stopper and crimp cap (850154P-100ug))
pkg of 1 × 500 μg (with stopper and crimp cap (850154P-500ug))

Fabricant/nom de marque

Avanti Research - A Croda Brand 850154P

Type de lipide

phospholipids
cardiolipins

Conditions d'expédition

dry ice

Température de stockage

−20°C

Chaîne SMILES 

[H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](OP(O)([O-])=O)[C@H](O)[C@@H](OP([O-])(O)=O)[C@H]1O)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[NH4+].[NH4+].[NH4+]

Description générale

Inositol phospholipid species are membrane-bound signaling molecules that have been implicated in almost all aspects of cellular physiology, including cellular growth, metabolism, proliferation, and survival.
Phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2), a phosphoinositideinositol phospholipid is mainly present in the membranes of endosome and lysosome of fungi and higher eukaryotes.

Application

18:1 PI(3,5)P2 (1,2-dioleoyl-sn-glycero-3-phospho-(1′-myo-inositol-3′,5′-bisphosphate) (ammonium salt)) may be used in vesicles for co-sedimentation assays. It has also been used:
  • in lipid overlay assay
  • in liposome co-sedimentation
  • in liposome flotation assays

Actions biochimiques/physiologiques

The level of phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2) surges in response to numerous extracellular stresses.

Conditionnement

2 mL Amber Serum Vial with Stopper and Crimp Cap (850154P-100ug)
2 mL Amber Serum Vial with Stopper and Crimp Cap (850154P-500ug)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

No data available

Point d'éclair (°C)

No data available


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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The Journal of biological chemistry, 293(13), 4818-4829 (2018-02-10)
Membrane phosphoinositides control organization and dynamics of the actin cytoskeleton by regulating the activities of several key actin-binding proteins. Twinfilin is an evolutionarily conserved protein that contributes to cytoskeletal dynamics by interacting with actin monomers, filaments, and the heterodimeric capping
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Neuron, 98(2), 335-349 (2018-04-03)
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