810606P
Avanti
16:0 Tempo PC
Avanti Research™ - A Croda Brand 810606P, powder
Synonyme(s) :
1,2-dipalmitoyl-sn-glycero-3-phospho(tempo)choline
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About This Item
Formule empirique (notation de Hill):
C48H94N2O9P
Numéro CAS:
Poids moléculaire :
874.24
Code UNSPSC :
41141825
Nomenclature NACRES :
NA.25
Produits recommandés
Pureté
>99% (TLC)
Forme
powder
Conditionnement
pkg of 1 × 1 mg (810606P-1mg)
Fabricant/nom de marque
Avanti Research™ - A Croda Brand 810606P
Type de lipide
phospholipids
ESR probes
Conditions d'expédition
dry ice
Température de stockage
−20°C
Catégories apparentées
Description générale
1,2-dipalmitoyl-sn-glycero-3-phospho(tempo)choline (16:0 Tempo PC) is a spin label phospholipid, where TEMPO moiety is attached to phosphocholine headgroup.
Application
1,2-dipalmitoyl-sn-glycero-3-phospho(tempo)choline (16:0 Tempo PC) may be used:
- as a spin-labeled quencher in liposomes to determine fluorophore depth
- as spin-labeled phospholipid along with 1,2-dimyristoyl(d54)-sn-glycero-3-phosphocholine-1,1,2,2-d4-N,N,N-trimethyl-d9 (DMPC-d67) to label lidocaine for paramagnetic relaxation measurements
- as a spin label to investigate the dependence of the packing and polarity of 1,2-dilauroyl-sn-glycero-3-phosphocholine (DLPC) bilayers with temperature or as quenchers of the Laurdan fluorescence to study the Laurdan position in fluid bilayers
Actions biochimiques/physiologiques
1,2-dipalmitoyl-sn-glycero-3-phospho(tempo)choline (16:0 Tempo PC/Tempo-PCSL) can effectively repress Laurdan fluorescence and can also quench the emission of long wavelength state.
Conditionnement
5 mL Clear Glass Sealed Ampule (810606P-1mg)
Informations légales
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 3
Point d'éclair (°F)
No data available
Point d'éclair (°C)
No data available
Certificats d'analyse (COA)
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Cíntia C De Vequi-Suplicy et al.
Journal of fluorescence, 16(3), 431-439 (2006-06-23)
Laurdan (2-dimethylamino-6-lauroylnaphthalene) is a hydrophobic fluorescent probe widely used in lipid systems. This probe was shown to be highly sensitive to lipid phases, and this sensitivity related to the probe microenvironment polarity and viscosity. In the present study, Laurdan was
Alexander Kyrychenko et al.
The Journal of membrane biology, 253(1), 73-77 (2019-09-22)
The characterization of the behavior of lipid-attached spin probes in a bilayer is of fundamental importance for correct interpretation of the results of both EPR and fluorescence studies of protein-membrane interactions. The knowledge of the immersion depth of TEMPO spin
Victor Vasquez-Montes et al.
Biochimica et biophysica acta. Proteins and proteomics, 1867(7-8), 691-700 (2019-04-21)
Bcl-xL is a member of the Bcl-2 family of apoptotic regulators, responsible for inhibiting the permeabilization of the mitochondrial outer membrane, and a promising anti-cancer target. Bcl-xL exists in the following conformations, each believed to play a role in the
Diego E Sastre et al.
The Journal of biological chemistry, 295(7), 2136-2147 (2019-12-05)
PlsX plays a central role in the coordination of fatty acid and phospholipid biosynthesis in Gram-positive bacteria. PlsX is a peripheral membrane acyltransferase that catalyzes the conversion of acyl-ACP to acyl-phosphate, which is in turn utilized by the polytopic membrane
Nicole Weizenmann et al.
Biochimica et biophysica acta, 1818(12), 3010-3018 (2012-07-31)
The membrane location of the local anesthetics (LA) lidocaine, dibucaine, tetracaine, and procaine hydrochloride as well as their influence on phospholipid bilayers were studied by ³¹P and ¹H magic-angle spinning (MAS) NMR spectroscopy. The ³¹P NMR spectra of the LA/lipid
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