QBD10009

Biotin-dPEG^®₄-TFP ester

• Synonyme(s) : Polyethylene glycol
• Formule empirique (notation de Hill): C₂₇H₃₇F₄N₃O₈S
• Poids moléculaire : 639.66
• Code UNSPSC : 12352108
• ID de substance PubChem : 329823873
• Nomenclature NACRES : NA.22

Propriétés

• Pureté: >90%
• Forme: solid or viscous liquid
• Capacité de réaction: reaction type: Biotinylations; reaction type: Biotinylations; reactivity: amine reactive
• Pertinence de la réaction: reagent type: cross-linking reagent
• Architecture des polymères: shape: linear; functionality: monofunctional
• Conditions d'expédition: ambient
• Température de stockage: −20°C
• Chaîne SMILES: O=C(CCCCC1SCC(N2)C1NC2=O)NCCOCCOCCOCCOCCC(OC3=C(C(F)=CC(F)=C3F)F)=O

Description

Application

Biotin-dPEG^®₄-TFP ester is an amphiphilic and hydrolytically stable compound used as a cross-linking reagent in biotinylations reactions.

Caractéristiques et avantages

Biotin-dPEG^®₄-TFP ester has 2,3,5,6-tetrafluorophenyl (TFP) moiety which hydrolyzes more slowly than NHS ester in aqueous media and are more reactive towards amines than NHS esters. The single molecular weight Biotin-dPEG^®₄-TFP ester has a long spacer of precise length (19.2 Å) between the biotin moiety and the labeled molecule. This dPEG spacer imparts a high degree of water solubility to the biotin label. The PEG spacer dramatically reduces aggregation and precipitation of the modified molecule and reduces non-specific binding of the molecule, both of which are common problems with molecules that have been biotinylated with the widely used NHS-LC-biotin.

Informations légales

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable