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914460

Sigma-Aldrich

1-Biotinyl-3,6-dioxa-8-octaneamine hydrochloride

≥95%

Synonyme(s) :

1-Biotinyl-3,6-dioxa-8-octaneamine hydrochloride, N-(2-(2-(2-aminoethoxy)ethoxy)ethyl)-5-(2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide hydrochloride, N-{2-[2-(2- Aminoethoxy)ethoxy]ethoxy}biotinamide hydrochloride, Amine-terminated biotin linker, Biotin-DOOA HCl, Biotinylation reagent

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About This Item

Formule empirique (notation de Hill):
C16H31ClN4O4S
Numéro CAS:
862373-14-6
Poids moléculaire :
410.96
Code UNSPSC :
12352116
Nomenclature NACRES :
NA.22

Niveau de qualité

100

Pureté

≥95%

Forme

powder

Température de stockage

2-8°C

Application

1-Biotinyl-3,6-dioxa-8-octaneamine hydrochloride is a versatile biotinylated linker that can be incorporated into chemical tools via its terminal amino group. Labeling materials or proteins with biotin provides a means to enrich and capture targets from biological systems.

Automate your Biotin tagging with Synple Automated Synthesis Platform (SYNPLE-SC002)

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Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

T2879

Tyramine hydrochloride, ≥98%

H1759

(+)-Biotin N-hydroxysuccinimide ester, ≥98% (HPLC), powder

B7639

(+)-Biotin hydrazide, ≥97% (TLC), powder

B5768

Biotin 4-amidobenzoic acid sodium salt, ≥95%

14400

Biotine, ≥99.0% (T)

861650

(+)-Biotin 4-nitrophenyl ester, 98%

B2059

Biotin Polyethyleneoxide Iodoacetamide

764213

Biotin-PEG4-alkyne, for copper catalyzed click labeling

QBD10196

Biotin-dPEG®11-NH2

QBD10826

Biotin-dPEG®7-NH2

SML2135

Biotinyl tyramide, ≥97% (HPLC)

914916

Biotin-SS-tyramide, ≥95%

914134

5-(Biotinamido)pentylamine TFA Salt, ≥95%

914924

3-[2-N-(Biotinyl)aminoethyldithio]propanoic acid, ≥95%

913669

Biotinamidoethyldisulfanyl(2-aminoethane) trifluoroacetic acid

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

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Sebastian Pomplun et al.
Angewandte Chemie (International ed. in English), 58(11), 3542-3547 (2019-01-18)
We discovered N-pyrrolyl alanine derivatives as efficient reagents for the fast and selective Pictet-Spengler reaction with aldehyde-containing biomolecules. Other aldehyde-labeling methods described so far have several drawbacks, like hydrolytic instability, slow reaction kinetics or not readily available labeling reagents. Pictet-Spengler
Benjamin Spangler et al.
ACS chemical biology, 14(4), 725-734 (2019-03-26)
Compartmentalization is a crucial facet of many biological systems, and key aspects of cellular processes rely on spatial segregation within the cell. While many drug targets reside in specific intracellular compartments, the tools available for assessing compound exposure are generally
Wilke C de Vries et al.
ACS applied materials & interfaces, 9(48), 41760-41766 (2017-11-16)
We present the preparation of ligand-conjugated redox-responsive polymer nanocontainers by the supramolecular decoration of cyclodextrin vesicles with a thin redox-cleavable polymer shell that displays molecular recognition units on its surface. Two widely different recognition motifs (mannose-Concanavalin A and biotin-streptavidin) are
Zhiyuan Fang et al.
Chemical communications (Cambridge, England), 49(55), 6164-6166 (2013-06-04)
A direct ELISA was established for the fast detection of semicarbazide (SEM) using a novel biotin derivative. Without a tedious extraction procedure, as low as 0.07 μg L(-1) of SEM could be detected reproducibly. This assay has better recovery and
Dilini N Kekulandara et al.
Biochemistry, 57(5), 772-780 (2017-12-21)
Thioredoxin 1 (Trx1) and glutaredoxin 1 (Grx1) are two ubiquitous redox enzymes that are central for redox homeostasis but also are implicated in many other processes, including stress sensing, inflammation, and apoptosis. In addition to their enzymatic redox activity, a
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