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Regenerez® Poly(glycerol sebacate) Resin

Synonyme(s) :

PGS, Poly(glycerol sebacic acid)

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About This Item

Formule linéaire :
(C13H22O5)n
Code UNSPSC :
12352200

Forme

paste

Niveau de qualité

Température de transition

flash point >230 °F

Température de stockage

−20°C

Application

Regenerez® Poly(glycerol sebacate) is a bioresorbable elastomer. The physical properties can be tuned from an elastomer to a thermoset(U.S. Patent No. 9.359,472) by curing PGS to the desired level of cross-linking. The inherent elastomeric properties of PGS can be used in a variety of applications in regenerative medicine and tissue engineering.

Caractéristiques et avantages

  • Bioresorbable.
  • Comprised of naturally occurring metabolites (glycerol and sebacic acid).
  • Tunable mechanical properties.
  • Versatile platform for further modification.
  • Closely simulates modulus of human tissue.
  • Enables healing without harmful immune response.

Informations légales

U.S. Patent No. 9,359,472.
Regenerez is a registered trademark of The Secant Group, LLC

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

No data available

Point d'éclair (°C)

No data available


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No satisfactory method currently exists for bridging neural defects. Autografts lead to inadequate functional recovery, and most available artificial neural conduits possess unfavorable swelling and pro-inflammatory characteristics. This study examined the biocompatibility of a novel biodegradable elastomer, poly(glycerol sebacate) (PGS)
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Host remodeling is important for the success of medical implants, including vascular substitutes. Synthetic and tissue-engineered grafts have yet to show clinical effectiveness in arteries smaller than 5 mm in diameter. We designed cell-free biodegradable elastomeric grafts that degrade rapidly
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For bone engineering, the optimal scaffolding material and composition has yet to be elucidated. In this study, we investigated poly (glycerol sebacate) (PGS), an elastomer known primarily for its soft tissue regeneration ability, as a suitable substrate to support osteo-precursor
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The objectives of this study were to evaluate the efficacy of poly(glycerol) sebacate (PGS) films for the prevention of visceroparietal peritoneal (VP) adhesions and demonstrate the ease of laparoscopic PGS film placement. Peritoneal adhesions occur in nearly 95% of all

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