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COO/COA

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484628

Benztropine mesylate

Name: Benztropine mesylate
Brand: ALDRICH

95%

Synonyme(s) :

Benztropine methanesulfonate

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About This Item

Formule empirique (notation de Hill):

C₂₁H₂₅NO

Numéro CAS:

132-17-2

Poids moléculaire :

307.43

Numéro CE :

205-048-8

Numéro MDL:

MFCD00074784

Code UNSPSC :

12352103

Pureté

95%

Pf

135 °C (lit.)

Chaîne SMILES

CS(O)(=O)=O.CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(c3ccccc3)c4ccccc4

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Pictogrammes

GHS06

Mention d'avertissement

Danger

Mentions de danger

H302,H311 + H331

Conseils de prudence

P261 - P264 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P311

Classification des risques

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 4 Oral

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

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Certificats d'analyse (COA)

Lot/Batch Number

20511TR

13802TR

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Interventions for drooling in children with cerebral palsy.

Margaret Walshe et al.

The Cochrane database of systematic reviews, 2(2), CD008624-CD008624 (2012-02-18)

Drooling is a common problem for children with cerebral palsy (CP). This can be distressing for these children as well as for their parents and caregivers. The consequences of drooling include risk of social rejection, damp and soiled clothing, unpleasant

A selective dopamine reuptake inhibitor improves prefrontal cortex-dependent cognitive function: potential relevance to attention deficit hyperactivity disorder.

Brooke E Schmeichel et al.

Neuropharmacology, 64, 321-328 (2012-07-17)

Drugs used to treat attention deficit hyperactivity disorder (ADHD) improve prefrontal cortex (PFC)-dependent cognitive function. The majority of ADHD-related treatments act either as dual norepinephrine (NE) and dopamine (DA) reuptake inhibitors (psychostimulants) or selective NE reuptake inhibitors (SNRIs). Certain benztropine

The stereotypy-inducing effects of N-substituted benztropine analogs alone and in combination with cocaine do not account for their blockade of cocaine self-administration.

Libin Li et al.

Psychopharmacology, 225(3), 733-742 (2012-09-15)

Previous studies have demonstrated that several N-substituted 4', 4″-diF-benztropine (BZT) analogs with high dopamine transporter affinity selectively decreased cocaine self-administration without affecting food-maintained behavior in rats. The present study examined if the decreases in cocaine self-administration are due to competition

Combinations of cocaine with other dopamine uptake inhibitors: assessment of additivity.

Gianluigi Tanda et al.

The Journal of pharmacology and experimental therapeutics, 330(3), 802-809 (2009-06-02)

Drugs that inhibit dopamine (DA) reuptake through actions at the dopamine transporter (DAT) have been proposed as candidates for development as pharmacotherapies for cocaine abuse. Accordingly, it is important to understand the potential pharmacological interactions of cocaine with other drugs

Assessment of reinforcing effects of benztropine analogs and their effects on cocaine self-administration in rats: comparisons with monoamine uptake inhibitors.

Takato Hiranita et al.

The Journal of pharmacology and experimental therapeutics, 329(2), 677-686 (2009-02-21)

Benztropine (BZT) analogs inhibit dopamine uptake but are less effective than cocaine in producing behavioral effects predicting abuse liability. The present study compared reinforcing effects of intravenous BZT analogs with those of standard monoamine uptake inhibitors and the effects of

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