406546
10-Undecynoic acid
95%
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5 G
128,00 €
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5 G
128,00 €
About This Item
Formule linéaire :
HC≡C(CH2)8CO2H
Numéro CAS:
Poids moléculaire :
182.26
Beilstein:
1704918
Numéro CE :
Numéro MDL:
Code UNSPSC :
12352100
ID de substance PubChem :
Nomenclature NACRES :
NA.22
Produits recommandés
Niveau de qualité
Essai
95%
pb
180 °C/15 mmHg (lit.)
Pf
40-42 °C (lit.)
Groupe fonctionnel
carboxylic acid
Chaîne SMILES
OC(=O)CCCCCCCCC#C
InChI
1S/C11H18O2/c1-2-3-4-5-6-7-8-9-10-11(12)13/h1H,3-10H2,(H,12,13)
Clé InChI
OAOUTNMJEFWJPO-UHFFFAOYSA-N
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Catégories apparentées
Description générale
10-Undecynoic acid (10- UDYA, UDY) is an acetylenic fatty acid. It is reported as highly selective irreversible inhibitor of hepatic ω- and ω-1-lauric acid hydroxylases.[1] Enzyme catalyzed esterification of 10-undecynoic acid has been reported.[2][3] UDY has been reported to be synthesized by the dehydrobromination of 10-undecenoic acid.[4]
Application
10-Undecynoic acid was employed as model compound to investigate the microwave assisted surface click reactions catalyzed with Cu(II)/sodium L-ascorbate.†
It may be used:
It may be used:
Mention d'avertissement
Warning
Mentions de danger
Conseils de prudence
Classification des risques
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Organes cibles
Respiratory system
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 3
Point d'éclair (°F)
235.4 °F - closed cup
Point d'éclair (°C)
113 °C - closed cup
Équipement de protection individuelle
dust mask type N95 (US), Eyeshields, Gloves
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The cytochrome P-450 eicosanoid 20-hydroxyeicosatetraenoic acid (20-HETE) is a potent vasoconstrictor that is implicated in the regulation of blood pressure. The identification of selective inhibitors of renal 20-HETE formation for use in vivo would facilitate studies to determine the systemic
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PloS one, 14(4), e0214763-e0214763 (2019-04-19)
In the search for novel agents against oral pathogens in their planktonic and biofilm form, we have focused our attention on 10-undecynoic acid as the representative of the acetylenic fatty acids. Using macro-broth susceptibility testing method we first established MIC
R C Zangar et al.
Archives of biochemistry and biophysics, 337(2), 217-224 (1997-01-15)
CYP2B, CYP4A, and CYP2E1 mRNA levels are elevated in response to pathophysiological conditions, such as diabetes, high-fat diet, and fasting, in which lipids and ketone bodies are increased. In order to avoid confounding hormonal effects, we utilized primary rat hepatocytes
P R Ortiz de Montellano et al.
The Journal of biological chemistry, 259(7), 4136-4141 (1984-04-10)
The terminal acetylenic analogue of lauric acid, 11-dodecynoic acid (11-DDYA), specifically inactivates hepatic cytochrome P-450 enzymes that catalyze omega- and omega-1-hydroxylation of lauric acid. The inactivation, as required for a suicidal process, is NADPH- and time-dependent and follows pseudo-first order
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