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329207

Sigma-Aldrich

Dianhydro-D-glucitol

98%

Synonyme(s) :

1,4:3,6-Dianhydro-D-sorbitol, D-Isosorbide

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Disponible pour expédition le18 avril 2025Détails


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500 G
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About This Item

Formule empirique (notation de Hill) :
C6H10O4
Numéro CAS:
Poids moléculaire :
146.14
Beilstein:
80510
Numéro CE :
Numéro MDL:
Code UNSPSC :
12352201
ID de substance PubChem :
Nomenclature NACRES :
NA.22

85,20 €


Disponible pour expédition le18 avril 2025Détails


Devis pour commande en gros

Essai

98%

Forme

solid

Activité optique

[α]20/D +45.2°, c = 3 in H2O

Pf

60-63 °C (lit.)

Chaîne SMILES 

O[C@H]1CO[C@@H]2[C@H](O)CO[C@H]12

InChI

1S/C6H10O4/c7-3-1-9-6-4(8)2-10-5(3)6/h3-8H,1-2H2/t3-,4+,5-,6-/m1/s1

Clé InChI

KLDXJTOLSGUMSJ-JGWLITMVSA-N

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Application

Dianhydro-D-glucitol is a greener ingredient widely used as a monomer and building block for a variety of polymers and functional materials, for medical and pharmaceutical applications.[1][2][3] It is also used as a fuel or fuel additive.[1]
Applications include:
  • Preparation of renewable polyesters for coating applications.[4]
  • Synthesis of isosorbide esters such as oligo(isosorbide adipate) (OSA), oligo(isosorbide suberate) (OSS), and isosorbide dihexanoate (SDH) as renewable alternatives to phthalate plasticizers.[5]
  • Synthesis of biodegradable porous polyurethane scaffolds for tissue repair and regeneration.[2]
  • Synthesis of the aspirin prodrug, isosorbide-2,5-diaspirinate (ISDA).[3]

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)


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Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

Kazunari Okada et al.
ORL; journal for oto-rhino-laryngology and its related specialties, 74(3), 158-163 (2012-05-16)
We used new criteria to elucidate the demographics of acute low-tone sensorineural hearing loss (ALHL) and tested the Chinese medicine Wu-Ling-San as a treatment for ALHL. We reviewed the medical records of patients with ALHL seen at the outpatient clinic
Biodegradable porous polyurethane scaffolds for tissue repair and regeneration.
Gorna, Katarzyna and Gogolewski, Sylwester
Journal of Biomedical Materials Research Part A, 79(1), 128-138 (2006)
Oligomeric isosorbide esters as alternative renewable resource plasticizers for PVC.
Yin, Bo and Hakkarainen, Minna
Journal of Applied Polymer Science, 119(4), 2400-2407 (2011)
Urgent need for WHO's reform to prioritise core functions.
Mohga Kamal-Yanni et al.
Lancet (London, England), 379(9829), 1878-1878 (2012-05-23)
Neal T Wasserman et al.
Veterinary ophthalmology, 16(1), 20-24 (2012-04-20)
To evaluate and compare the effects of oral isosorbide and glycerol on intraocular pressure (IOP), serum osmolality (SOSM), and blood glucose (BG) in normal dogs. Ten normal dogs were administered an oral dose of either isosorbide (1.5 g/kg), glycerol (1.5g/kg)

Questions

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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 réponse
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 réponse
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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