32596

Diallyl pyrocarbonate

≥95.0% (T)

• Synonyme(s) : (Alloc)₂O, Diallyl dicarbonate
• Formule linéaire : (CH₂=CHCH₂OCO)₂O
• Numéro CAS: 115491-93-5
• Poids moléculaire : 186.16
• Numéro Beilstein : 4390381
• Numéro MDL: MFCD00077721
• Code UNSPSC : 12352108
• ID de substance PubChem : 57648690

Propriétés

• Pureté: ≥95.0% (T)
• Indice de réfraction: n20/D 1.434 (lit.); n20/D 1.434
• Point d'ébullition: 60 °C/0.05 mmHg (lit.)
• Densité: 1.121 g/mL at 25 °C (lit.)
• Application(s): peptide synthesis
• Température de stockage: 2-8°C
• Chaîne SMILES: C=CCOC(=O)OC(=O)OCC=C
• InChI: 1S/C8H10O5/c1-3-5-11-7(9)13-8(10)12-6-4-2/h3-4H,1-2,5-6H2
• Clé InChI: XVSSGIXTKVRGAR-UHFFFAOYSA-N

Description

Description générale

Diallyl pyrocarbonate or (Alloc)₂O is used as a reagent for the introduction of allyloxycarbonyl (Alloc or Aloc) protecting group to primary and secondary amines. In peptide synthesis, it is also used to protect amino acid functional groups due to its stability to the acidic and basic conditions. Various amino functional groups such as amino sugars and nucleosides are also protected by using diallyldicarbonate reagent.

Autres remarques

Reagent for the convenient introduction of the N-allyloxycarbonyl (N-Alloc) amino protection ; Allyl carbamate protections can be readily cleaved by palladium(0) reagents.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H315,H319,H335
• Conseils de prudence: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classification des risques: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): 201.2 °F - closed cup
• Point d'éclair (°C): 94 °C - closed cup
• Équipement de protection individuelle: Eyeshields, Gloves, type ABEK (EN14387) respirator filter