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275581

Sigma-Aldrich

6-Aminoquinoline

98%

Synonyme(s) :

6-Quinolinamine

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About This Item

Formule empirique (notation de Hill):
C9H8N2
Numéro CAS:
580-15-4
Poids moléculaire :
144.17
Numéro Beilstein :
113320
Numéro CE :
209-453-0
Numéro MDL:
MFCD00006803
Code UNSPSC :
12352100
ID de substance PubChem :
24856657
Nomenclature NACRES :
NA.22

Pureté

98%

Forme

solid

Point d'ébullition

146 °C/0.3 mmHg (lit.)

Pf

115-119 °C (lit.)

Chaîne SMILES 

Nc1ccc2ncccc2c1

InChI

1S/C9H8N2/c10-8-3-4-9-7(6-8)2-1-5-11-9/h1-6H,10H2

Clé InChI

RJSRSRITMWVIQT-UHFFFAOYSA-N

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Application

6-Aminoquinoline was used as an internal standard in determining serum nicotine and cotinine simultaneously by using high-performance liquid chromatography (HPLC)-fluorometric detection with a postcolumn ultraviolet-photoirradiation system. It was also used as a fluorescent derivatizing agent for the detection of biochemicals and in the synthesis of tertiary N-methylated enaminonesa.

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H315,H319

Classification des risques

Eye Irrit. 2 - Skin Irrit. 2

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Gloves

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Consulter la Bibliothèque de documents

Pierre-Jean Aragon et al.
Chemical & pharmaceutical bulletin, 52(6), 659-663 (2004-06-10)
Indoloquinoline alkaloid cryptolepine and pyridocarbazole alkaloid ellipticine are of great interest because in vitro and in vivo studies revealed their good cytotoxic properties. In order to obtain some biologically active analogs of these compounds, we developped a synthesis based on
Bryan P Ruddy et al.
Journal of controlled release : official journal of the Controlled Release Society, 306, 83-88 (2019-06-01)
Subcutaneous delivery of nicotine was performed using a novel electrically-operated needle-free jet injector, and compared to hypodermic needle delivery in a porcine model. Nicotine was delivered as a single, one-milligram dose into the abdominal skin, formulated as a 50 microliter
Jong Bae Seo et al.
PloS one, 10(12), e0144432-e0144432 (2015-12-15)
Hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) of the plasma membrane by phospholipase C (PLC) generates two critical second messengers, inositol-1,4,5-trisphosphate and diacylglycerol. For the enzymatic reaction, PIP2 binds to positively charged amino acids in the pleckstrin homology domain of PLC. Here
W Nashabeh et al.
Journal of chromatography, 600(2), 279-287 (1992-05-29)
The electrophoretic behavior of derivatized linear and branched oligosaccharides from various sources was examined in capillary zone electrophoresis with polyether-coated fused-silica capillaries. Two UV-absorbing (also fluorescent) derivatizing agents (2-aminopyridine and 6-aminoquinoline) were utilized for the electrophoresis and sensitive detection of
S A Cohen et al.
Analytical biochemistry, 211(2), 279-287 (1993-06-01)
A highly reactive amine derivatizing reagent, 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate, has been synthesized. In a rapid, one-step procedure, the compound reacts with amino acids to form stable unsymmetric urea derivatives which are readily amenable to analysis by reversed phase HPLC. Studies on
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