International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes, 39(10), 1023-1027 (1988-01-01)
Ruthenocene amphetamine analogues have the same brain uptake as iodo-labelled amphetamines. This paper compares the organ-distribution of 103Ru labelled ruthenocene- or ferrocene-amphetamine analogues in mice and rats with the same amphetamine in which H-atoms were partly substituted by D-atoms. The
Journal of medicinal chemistry, 48(11), 3696-3699 (2005-05-27)
Metallocene-derived bioisosteres lead to exceptionally strong binding G-protein-coupled receptor ligands, indicating substantial plasticity of the receptor excluded volume. Novel binding profiles of ferrocenylcarboxamides combining subnanomolar Ki values for the dopamine D4 receptor (1a, 0.52 nM; 1b, 0.63 nM) with superpotent
Dalton transactions (Cambridge, England : 2003), 40(6), 1382-1386 (2010-12-25)
Organometallic conjugates of receptor-targeting peptides are proposed as interesting candidates for novel cancer therapies since they are capable of targeting a specific kind of cell. Here, we have synthesised a dicobalt hexacarbonyl alkyne compound linked to the neurotensin peptide hormone.
(D)-Biotin was used for Friedel-Crafts acylation of electron-rich aromatic molecules--ferrocene, ruthenocene and pyrene. The reaction carried out in the presence of trifluoroacetic anhydride and trifluoromethanesulfonic acid afforded the corresponding biotinylarenes in moderate yields. These compounds, although lacking an amide bond
[Metabolism of 103 Ru-ruthenocene--in vitro experiments and a possible in vivo test for hydroxylases].
M Wenzel et al.
The International journal of applied radiation and isotopes, 32(11), 797-802 (1981-11-01)
Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..
