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Merck

SLC1A2

solute carrier family 1 (glial high affinity glutamate transporter), member 2

Synonymes:
EAAT2, GLT-1
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(6506) Summary: This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis. Alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Sep 2010]
  • Mouse(20511) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • Rat(29482) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • naked mole-rat(101701278) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • domestic guinea pig(100731435) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • chicken(423156) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • dog(403750) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • cow(541119) solute carrier family 1 (glial high affinity glutamate transporter), member 2

Custom & Knockdown Gene Products

Small Molecule - Antagonist

Numéro du produit
Description
Espèce(s)
L-trans-Pyrrolidine-2,4-dicarboxylic acid, ≥98%,
Espèce(s)
rat
Dihydrokainic acid, ≥98% (HPLC), powder,
Espèce(s)
rat, human
(±)-AMPA, solid,
Espèce(s)
rat
Acide (Aminométhyl)phosphonique, 99%,
Espèce(s)
rat, human
L-Glutamic acid, ReagentPlus®, ≥99% (HPLC),
Espèce(s)
rat, human

Antibodies

Numéro du produit
Description
Espèces réactives
Application
Anticorps anti-transporteur du glutamate glial, serum, Chemicon®,
Espèces réactives
human, mouse, rat
Application
immunofluorescence
immunohistochemistry

western blot
Anti-SLC1A2 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
immunohistochemistry
western blot
Anti-Excitatory amino acid transporter 2 Antibody, clone G6, clone G6, from mouse,
Espèces réactives
human, mouse, rat
Application
immunocytochemistry
immunohistochemistry

western blot
Anti-SLC1A2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
Anti-Excitatory Amino Acid Transporter (GLT-1) Rabbit pAb, liquid, Calbiochem®,
Espèces réactives
rat
Application

Small Molecule - Inhibitor

Numéro du produit
Description
Espèce(s)
Dihydrokainic acid, ≥98% (HPLC), powder,
Espèce(s)
rat, human
Acide (Aminométhyl)phosphonique, 99%,
Espèce(s)
rat, human
L-Glutamic acid, ReagentPlus®, ≥99% (HPLC),
Espèce(s)
rat, human
L-Glutamic acid, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
Espèce(s)
rat, human
L-Glutamic acid, BioUltra, ≥99.5% (NT),
Espèce(s)
rat, human

esiRNA

Numéro du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human SLC1A2,
Espèce(s)
human