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Merck

SLC18A2

solute carrier family 18 (vesicular monoamine transporter), member 2

Synonymes:
SVAT, SVMT, VAT2, VMAT2
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(6571) Summary: The vesicular monoamine transporter acts to accumulate cytosolic monoamines into synaptic vesicles, using the proton gradient maintained across the synaptic vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (summary by Peter et al., 1993 [PubMed 7905859]
  • Mouse(214084) solute carrier family 18 (vesicular monoamine), member 2
  • Rat(25549) solute carrier family 18 (vesicular monoamine transporter), member 2
  • Horse(100058805) solute carrier family 18 (vesicular monoamine), member 2
  • cow(282471) solute carrier family 18 (vesicular monoamine), member 2
  • domestic guinea pig(100719098) solute carrier family 18 (vesicular monoamine), member 2
  • domestic cat(101086507) solute carrier family 18 (vesicular monoamine), member 2
  • dog(486908) solute carrier family 18 (vesicular monoamine), member 2
  • naked mole-rat(101725597) solute carrier family 18 (vesicular monoamine), member 2
  • chicken(423921) solute carrier family 18 (vesicular monoamine), member 2
  • sheep(101104796) solute carrier family 18 (vesicular monoamine), member 2
  • Zebrafish(553304) solute carrier family 18 (vesicular monoamine), member 2

Custom & Knockdown Gene Products

Antibodies

Numéro du produit
Description
Espèces réactives
Application
Anti-Vesicular Monoamine Transporter 2 Antibody, Chemicon®, from rabbit,
Espèces réactives
rat
Application
ELISA
immunohistochemistry

western blot
Anti-VMAT2/SLC18A2 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
human, rat
Application
ELISA
immunohistochemistry

western blot
Anti-SLC18A2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunohistochemistry
Anti-SLC18A2 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL12531, purified by using Protein A, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
Anti-SLC18A2 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL13157, purified by using Protein A, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
western blot

Small Molecule - Inhibitor

Numéro du produit
Description
Espèce(s)
S(+)-Amphetamine (dextro-Amphetamine) solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Espèce(s)
human
Reserpine, crystallized, ≥99.0% (HPLC),
Espèce(s)
human
Lisdexamfetamine dimesylate solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Espèce(s)
human
Dextroamphetamine sulfate, United States Pharmacopeia (USP) Reference Standard, monograph mol wt. 368.49 ((C9H13N)2 · H2SO4),
Espèce(s)
human
Dexamfetamine sulfate, European Pharmacopoeia (EP) Reference Standard,
Espèce(s)
human

esiRNA

Numéro du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human SLC18A2,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Slc18a2,
Espèce(s)
mouse