Accéder au contenu
Merck

SCN8A

sodium channel, voltage gated, type VIII, alpha subunit

Synonymes:
CERIII, CIAT, EIEE13, MED, NaCh6, Nav1.6, PN4
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(6334) Summary: This gene encodes a member of the sodium channel alpha subunit gene family. The encoded protein forms the ion pore region of the voltage-gated sodium channel. This protein is essential for the rapid membrane depolarization that occurs during the formation of the action potential in excitable neurons. Mutations in this gene are associated with mental retardation, pancerebellar atrophy and ataxia. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
  • Mouse(20273) sodium channel, voltage-gated, type VIII, alpha
  • Rat(29710) sodium channel, voltage gated, type VIII, alpha subunit
  • chicken(100857835) sodium channel, voltage gated, type VIII, alpha subunit
  • dog(477604) sodium channel, voltage gated, type VIII, alpha subunit
  • Horse(100052777) sodium channel, voltage gated, type VIII, alpha subunit
  • cow(537277) sodium channel, voltage gated, type VIII, alpha subunit
  • naked mole-rat(101711868) sodium channel, voltage gated, type VIII, alpha subunit
  • domestic guinea pig(100734003) sodium channel, voltage gated, type VIII, alpha subunit
  • sheep(101113744) sodium channel, voltage gated, type VIII, alpha subunit
  • domestic cat(101096578) sodium channel, voltage gated, type VIII, alpha subunit
  • chicken(426869) sodium channel, voltage gated, type VIII, alpha subunit

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Référence du produit
Description
Espèces réactives
Application
Monoclonal Anti-SCN8A antibody produced in mouse, clone 4G7, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human, mouse, rat
Application
ELISA
immunofluorescence

western blot
Anti-SCN8A Sodium Channel Antibody, Chemicon®, from rabbit,
Espèces réactives
mouse, rat
Application
immunocytochemistry
immunohistochemistry

western blot
Anti-SCN8A, affinity isolated antibody,
Espèces réactives
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
Anti-SCN8A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
Anti-SCN8A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence

Small Molecule - Blocker

Référence du produit
Description
Espèce(s)
Lidocaine hydrochloride monohydrate, solid,
Espèce(s)
human
Procaine hydrochloride, ≥97%,
Espèce(s)
human
Lidocaine hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human
Lidocaine, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human
Procainamide hydrochloride, ≥98% (HPLC),
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Scn8a,
Espèce(s)
mouse