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Merck

MMP13

matrix metallopeptidase 13 (collagenase 3)

Synonymes:
CLG3, MANDP1
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(4322) Summary: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]
  • Mouse(17386) matrix metallopeptidase 13
  • Rat(171052) matrix metallopeptidase 13
  • naked mole-rat(101699013) matrix metallopeptidase 13 (collagenase 3)
  • sheep(443113) matrix metallopeptidase 13 (collagenase 3)
  • cow(281914) matrix metallopeptidase 13 (collagenase 3)
  • Domestic Rabbit(100008685) matrix metallopeptidase 13 (collagenase 3)
  • domestic guinea pig(100731756) matrix metallopeptidase 13 (collagenase 3)
  • chicken(395683) matrix metallopeptidase 13 (collagenase 3)
  • domestic cat(493679) matrix metallopeptidase 13 (collagenase 3)
  • dog(403763) matrix metallopeptidase 13 (collagenase 3)
  • Horse(100009711) matrix metallopeptidase 13 (collagenase 3)

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ELISA

Référence du produit
Description
Espèce(s)
Human MMP-13 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Espèce(s)
human

Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-MMP-13 Antibody, clone 181-15A12, clone 181-15A12, Chemicon®, from mouse,
Espèces réactives
human
Application
ELISA
immunohistochemistry

western blot
Anti-MMP-13 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti- MMP13 antibody produced in rabbit, ,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-MMP13 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
guinea pig, horse, human, rabbit, rat
Application
western blot
Anti-MMP-13 Antibody, clone VIIIA2, clone VIIIA2, Chemicon®, from mouse,
Espèces réactives
human, mouse, rabbit
Application
immunohistochemistry

Small Molecule - Inhibitor

Référence du produit
Description
Espèce(s)
Doxycycline monohydrate, ,
Espèce(s)
human
Doxycycline Monohydrate, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human
Marimastat, ≥98% (HPLC),
Espèce(s)
human, rat, mouse
CP-101537, ≥98% (HPLC),
Espèce(s)
human, rat, mouse
CP-471474, ≥98% (HPLC),
Espèce(s)
human, rat, mouse

Proteins

Référence du produit
Description
Espèce(s)
MMP-13, human, proform, his-tagged, E. coli recombinant, ,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human MMP13,
Espèce(s)
human