MBP
myelin basic protein
Synonymes:
Espèce(s):
Human MBP (4155), Mouse Mbp (17196), Rat Mbp (24547), chicken MBP (396217), domestic cat MBP (101096421), dog MBP (476160), sheep MBP (101109407), cow MBP (618684), naked mole-rat Mbp (101702488), domestic guinea pig Mbp (100731253)
ID UniProtKB:
ID du gène:
- Human(4155) Summary: The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called 'Golli-MBP') that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes. [provided by RefSeq, Jul 2008]
- Mouse(17196) myelin basic protein
- Rat(24547) myelin basic protein
- chicken(396217) myelin basic protein
- domestic cat(101096421) myelin basic protein
- dog(476160) myelin basic protein
- sheep(101109407) myelin basic protein
- cow(618684) myelin basic protein
- naked mole-rat(101702488) myelin basic protein
- domestic guinea pig(100731253) myelin basic protein
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Référence du produit
Description
Espèces réactives
Application
Monoclonal Anti-MBP antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2829, purified immunoglobulin, buffered aqueous glycerol solution,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Anti-Myelin Basic Protein Mouse mAb (SMI-99), liquid, clone SMI-99, Calbiochem®,
Espèces réactives
guinea pig, mammals
Application
Monoclonal Anti-MBP antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2827, purified immunoglobulin, buffered aqueous glycerol solution,
Espèces réactives
human, mouse, rat
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-MBP, affinity isolated antibody,
Espèces réactives
dog, guinea pig, horse, human, rabbit, rat
Application
western blot
Monoclonal Anti-Myelin Basic Protein (MBP) (36-50) antibody produced in rat, clone 14, tissue culture supernatant,
Espèces réactives
chicken, horse, human
Application
ELISA
immunofluorescence
immunohistochemistry
immunofluorescence
immunohistochemistry
Proteins
Référence du produit
Description
Espèce(s)
Protéine basique de la myéline bovine, ≥90% (SDS-PAGE), lyophilized powder, suitable for activity assay,
Espèce(s)
cow
Myelin Basic Protein from guinea pig brain, ≥80% (SDS-PAGE), lyophilized powder, from guinea pig brain,
Espèce(s)
domestic guinea pig
esiRNA
Référence du produit
Description
Espèce(s)