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Merck

CXCR3

chemokine (C-X-C motif) receptor 3

Synonymes:
CD182, CD183, CKR-L2, CMKAR3, GPR9, IP10-R, Mig-R, MigR
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(2833) Summary: This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716). [provided by RefSeq, Jun 2011]
  • Mouse(12766) chemokine (C-X-C motif) receptor 3
  • Rat(84475) chemokine (C-X-C motif) receptor 3
  • domestic cat(101094573) chemokine (C-X-C motif) receptor 3
  • dog(491952) chemokine (C-X-C motif) receptor 3
  • Goat(100860874) chemokine (C-X-C motif) receptor 3
  • cow(497018) chemokine (C-X-C motif) receptor 3
  • sheep(101107671) chemokine (C-X-C motif) receptor 3
  • naked mole-rat(101722797) chemokine (C-X-C motif) receptor 3
  • domestic guinea pig(100735932) chemokine (C-X-C motif) receptor 3

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-CXCR3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
Anti-CXCR3 antibody produced in rabbit, ,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-CXCR3 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
immunocytochemistry

immunofluorescence

western blot
Anti-CXC Chemokine Receptor 3 Antibody, CT domain, Chemicon®, from rabbit,
Espèces réactives
human
Application
immunohistochemistry
Monoclonal Anti-CXCR3 antibody produced in mouse, clone 49801.111, purified immunoglobulin, lyophilized powder,
Espèces réactives
human
Application
flow cytometry

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human CXCR3,
Espèce(s)
human