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Merck

CHRM3

cholinergic receptor, muscarinic 3

Synonymes:
EGBRS, HM3
Espèce(s):
Human CHRM3 (1131), Mouse Chrm3 (12671), Rat Chrm3 (24260), Domestic Rabbit CHRM3 (100355313), sheep CHRM3 (443189), domestic cat CHRM3 (101100919), cow CHRM3 (281685), Horse CHRM3 (100056633), dog CHRM3 (403827), domestic guinea pig Chrm3 (100379235)
ID UniProtKB:
P20309, Q0VAJ8, Q4QRI3, Q5VXY2, Q9HB60
ID du gène:
  • Human(1131) Summary: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 3 controls smooth muscle contraction and its stimulation causes secretion of glandular tissue. [provided by RefSeq, Jul 2008]
  • Mouse(12671) cholinergic receptor, muscarinic 3, cardiac
  • Rat(24260) cholinergic receptor, muscarinic 3
  • Domestic Rabbit(100355313) cholinergic receptor, muscarinic 3
  • sheep(443189) cholinergic receptor, muscarinic 3
  • domestic cat(101100919) cholinergic receptor, muscarinic 3
  • cow(281685) cholinergic receptor, muscarinic 3
  • Horse(100056633) cholinergic receptor, muscarinic 3
  • dog(403827) cholinergic receptor, muscarinic 3
  • domestic guinea pig(100379235) cholinergic receptor, muscarinic 3, cardiac
  • chicken(396364) cholinergic receptor, muscarinic 3

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Small Molecule - Agonist

Numéro du produit
Description
Espèce(s)
A6625
Chlorure d′acétylcholine, ≥99% (TLC),
Espèce(s)
human
A2661
Chlorure d′acétylcholine, suitable for cell culture,
Espèce(s)
human
A7000
Acetylcholine iodide, ≥97%,
Espèce(s)
human
A9101
Chlorure d′acétylcholine, pkg of 150 mg (per vial),
Espèce(s)
human
PHR1511
Carbachol, Pharmaceutical Secondary Standard; Certified Reference Material,
Espèce(s)
human

Small Molecule - Antagonist

Numéro du produit
Description
Espèce(s)
1347507
Ipratropium bromide, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human
1699005
Tropicamide, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human
1156000
Cyclopentolate hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human
I0360000
Ipratropium bromide, European Pharmacopoeia (EP) Reference Standard,
Espèce(s)
human
C3245000
Cyclopentolate hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Espèce(s)
human

Antibodies

Numéro du produit
Description
Espèces réactives
Application
AB9018
Anti-Muscarinic Acetylcholine Receptor m3 Antibody, Chemicon®, from rabbit,
Espèces réactives
rat
Application
western blot
HPA024106
Anti-CHRM3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
SAB5700750
Anti-CHRM3 antibody produced in rabbit, ,
Espèces réactives
human, mouse, rat
Application
western blot
M0194
Anti-Muscarinic Acetylcholine Receptor (M3) antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Espèces réactives
human, mouse, rat
Application
western blot

Small Molecule - Inhibitor

Numéro du produit
Description
Espèce(s)
A8404
Amitriptyline hydrochloride, ≥98% (TLC), powder,
Espèce(s)
human
D4526
Doxepin hydrochloride, ~85% E-isomer basis, ≥98% (GC), 15% Z-isomer basis, powder,
Espèce(s)
human
51330
Harmaline, ≥95%,
Espèce(s)
human, rat

Small Molecule - Ligand

Numéro du produit
Description
Espèce(s)
A138
Aminobenztropine, solid,
Espèce(s)
human

esiRNA

Numéro du produit
Description
Espèce(s)
EHU027151
MISSION® esiRNA, targeting human CHRM3,
Espèce(s)
human