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Merck

ADAM17

ADAM metallopeptidase domain 17

Synonymes:
ADAM18, CD156B, CSVP, NISBD, TACE
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(6868) Summary: This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway. [provided by RefSeq, Jul 2008]
  • Mouse(11491) a disintegrin and metallopeptidase domain 17
  • Rat(57027) ADAM metallopeptidase domain 17
  • sheep(101116815) ADAM metallopeptidase domain 17
  • naked mole-rat(101720924) ADAM metallopeptidase domain 17
  • domestic guinea pig(100732916) ADAM metallopeptidase domain 17
  • chicken(421931) ADAM metallopeptidase domain 17
  • domestic cat(101089004) ADAM metallopeptidase domain 17
  • dog(475662) ADAM metallopeptidase domain 17
  • cow(517541) ADAM metallopeptidase domain 17
  • Horse(100072496) ADAM metallopeptidase domain 17

Custom & Knockdown Gene Products

ELISA

Numéro du produit
Description
Espèce(s)
Human TACE ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Espèce(s)
human

Antibodies

Numéro du produit
Description
Espèces réactives
Application
Anti-TACE Antibody, clone D1(A12), clone D1(A12), from human(Recombinant),
Espèces réactives
human
Application
flow cytometry
Anti-ADAM 17 Antibody, Chemicon®, from rabbit,
Espèces réactives
human, mouse, rat
Application
immunocytochemistry
western blot
Anti-phospho-ADAM 17 (pThr735) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
western blot
Anti-Adam17 Antibody, serum, from rabbit,
Espèces réactives
human
Application
immunocytochemistry
western blot
Anti-ADAM17 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry

esiRNA

Numéro du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human ADAM17,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Adam17,
Espèce(s)
mouse