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Merck

ABCD3

ATP-binding cassette, sub-family D (ALD), member 3

Synonymes:
ABC43, PMP70, PXMP1, ZWS2
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(5825) Summary: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein likely plays an important role in peroxisome biogenesis. Mutations have been associated with some forms of Zellweger syndrome, a heterogeneous group of peroxisome assembly disorders. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(19299) ATP-binding cassette, sub-family D (ALD), member 3
  • Rat(25270) ATP-binding cassette, subfamily D (ALD), member 3
  • cow(526059) ATP-binding cassette, sub-family D (ALD), member 3
  • domestic cat(101100069) ATP-binding cassette, sub-family D (ALD), member 3
  • dog(479939) ATP-binding cassette, sub-family D (ALD), member 3
  • domestic guinea pig(100725969) ATP-binding cassette, sub-family D (ALD), member 3
  • chicken(424487) ATP-binding cassette, sub-family D (ALD), member 3
  • naked mole-rat(101702609) ATP-binding cassette, sub-family D (ALD), member 3
  • Domestic Rabbit(100351172) ATP-binding cassette, sub-family D (ALD), member 3
  • Horse(100058542) ATP-binding cassette, sub-family D (ALD), member 3
  • sheep(101118659) ATP-binding cassette, sub-family D (ALD), member 3

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-ABCD3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
Anti-ABCD3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
Anti-PMP70/ABCD3 Antibody, clone 3V4K3, Rabbit Monoclonal, ,
Espèces réactives
human, rat
Application
immunofluorescence
western blot
Anti-PMP70 antibody, Mouse monoclonal, clone 70-18, purified from hybridoma cell culture,
Espèces réactives
human, mouse, rat
Application
immunofluorescence
western blot
Anti-PMP70 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
human, mouse, rat
Application
immunofluorescence
immunoprecipitation (IP)

western blot

Proteins

Référence du produit
Description
Espèce(s)
Monoclonal Anti-ABCD3 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2524, purified immunoglobulin, buffered aqueous glycerol solution,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Abcd3,
Espèce(s)
mouse
MISSION® esiRNA, targeting human ABCD3,
Espèce(s)
human