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T8786

Sigma-Aldrich

Thr-Phe-Gln-Ala-Tyr-Pro-Leu-Arg-Glu-Ala

≥97% (HPLC)

Synonym(s):

H-Thr-Phe-Gln-Ala-Tyr-Pro-Leu-Arg-Glu-Ala-OH

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About This Item

Empirical Formula (Hill Notation):
C55H82N14O16
CAS Number:
117592-22-0
Molecular Weight:
1195.32
MDL number:
MFCD00076836
UNSPSC Code:
12352200
PubChem Substance ID:
24900562
NACRES:
NA.26

Assay

≥97% (HPLC)

storage temp.

−20°C

SMILES string

CC(C)CC(NC(=O)C1CCCN1C(=O)C(Cc2ccc(O)cc2)NC(=O)C(C)NC(=O)C(CCC(N)=O)NC(=O)C(Cc3ccccc3)NC(=O)C(N)C(C)O)C(=O)NC(CCCNC(N)=N)C(=O)NC(CCC(O)=O)C(=O)NC(C)C(O)=O

InChI

1S/C55H82N14O16/c1-28(2)25-38(49(79)63-35(13-9-23-60-55(58)59)48(78)64-37(20-22-43(73)74)47(77)62-30(4)54(84)85)66-51(81)41-14-10-24-69(41)53(83)40(27-33-15-17-34(71)18-16-33)68-45(75)29(3)61-46(76)36(19-21-42(56)72)65-50(80)39(26-32-11-7-6-8-12-32)67-52(82)44(57)31(5)70/h6-8,11-12,15-18,28-31,35-41,44,70-71H,9-10,13-14,19-27,57H2,1-5H3,(H2,56,72)(H,61,76)(H,62,77)(H,63,79)(H,64,78)(H,65,80)(H,66,81)(H,67,82)(H,68,75)(H,73,74)(H,84,85)(H4,58,59,60)

InChI key

GNKMMPBLQYIPCI-UHFFFAOYSA-N

Substrates

Retroviral protease substrate

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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M Kotler et al.
Proceedings of the National Academy of Sciences of the United States of America, 85(12), 4185-4189 (1988-06-01)
Processing of the gag and pol gene precursor proteins of retroviruses is essential for infectivity and is directed by a viral protease that is itself included in one of these precursors. We demonstrate here that small synthetic peptides can be

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