T7681
Tropine 2-(4-chlorophenoxy)butanoate maleate salt
≥98%
Synonym(s):
SM21
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About This Item
Empirical Formula (Hill Notation):
C18H24ClNO3 · C4H4O4
CAS Number:
Molecular Weight:
453.91
MDL number:
UNSPSC Code:
12352200
Assay
≥98%
storage temp.
2-8°C
SMILES string
OC(=O)\C=C/C(O)=O.CCC(Oc1ccc(Cl)cc1)C(=O)O[C@@H]2C[C@@H]3CC[C@H](C2)N3C
Biochem/physiol Actions
Potent analgesic. Causes increased release of acetylcholine at central muscarinic synapses.
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F Gualtieri et al.
Journal of medicinal chemistry, 37(11), 1712-1719 (1994-05-27)
Further modifications of the leads ((R)-(+)-hyoscyamine and (p-chlorophenyl)propionic acid alpha-tropanyl ester), which show analgesic and nootropic activities as a consequence of increased central presynaptic ACh release, are reported. 2-Phenoxy- and 2-(phenylthio)alkanoic acid esters showed the best results. Several members of
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