SRP0377
PLU-1 human
recombinant, expressed in baculovirus infected Sf9 cells, ≥55% (SDS-PAGE)
Synonym(s):
JARID1B, KDM5B, lysine (K)-specific demethylase 5B
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About This Item
biological source
human
recombinant
expressed in baculovirus infected Sf9 cells
Assay
≥55% (SDS-PAGE)
form
aqueous solution
mol wt
88 kDa
packaging
pkg of 20 μg
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... KDM5B(10765)
General description
Human Plu-1, also known as JARID1B and KDM5B (GenBank Accession No. NM_006618), amino-acids 2-751 with N-terminal HIS-FLAG-tag, MW=88 kDa, expressed in Sf9 cells via a Baculovirus expression system.
Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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Molecular cell, 25(6), 801-812 (2007-03-17)
Posttranslational modification of chromatin by histone methylation has wide-ranging effects on nuclear function, including transcriptional regulation, maintenance of genome integrity, and epigenetic inheritance. The enzymes utilized to place histone methylation marks are well characterized, but the identity of a histone
International journal of cancer, 121(2), 265-275 (2007-03-22)
The PLU-1/JARID1B nuclear protein, which is expressed in a high proportion of breast cancers, but shows restricted expression elsewhere, belongs to the ARID family of proteins, known to play important roles in development, differentiation, transcriptional regulation and chromatin remodeling. PLU-1/JARID1B
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