SAB5700124

Anti-TriMethyl-Histone H3-K27 antibody produced in mouse

• Synonym(s): H3.4, H3/g, H3FT, H3t, HIST1H3A, HIST3H3, Histone H3
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: mouse
• Quality Level: 100
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: monoclonal
• form: buffered aqueous solution
• mol wt: 15
• species reactivity: human, rat, mouse
• concentration: 3.96 mg/ml
• technique(s): ChIP: 1:20-1:100; immunofluorescence: 1:50-1:200; immunohistochemistry: 1:50-1:200; immunoprecipitation (IP): 1:50-1:200; western blot: 1:500-1:2000
• UniProt accession no.: Q16695
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: trimethylation (Lys27)
• Gene Information: human ... H3-4(8290)

Description

General description

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.

Immunogen

A synthetic methylated peptide corresponding to residues surrounding K27 of human histone H3

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable